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General Information
Symbol
Dmel\osk2
Species
D. melanogaster
Name
FlyBase ID
FBal0013304
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
osk84, osk084
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

C8936153T

Reported nucleotide change:

C1336T

Amino acid change:

R254term | osk-PA; R116term | osk-PC

Reported amino acid change:

R254term

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Nucleotide substitution: C1336T.

Amino acid replacement: R254term.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Dvir\oskvirosk provides poterior body patterning to osk2 and osk6 embryos, but in some instances the activity has spread towards the anterior of the embryo.

Lack posterior body pattern elements and germ cells.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement
Reference

btz1, osk2 has abdominal segment phenotype, enhanceable by CG748319

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Embryos produced by btz1 females with one copy of osk2 show a partial loss of abdominal segments. This phenotype is enhanced by the presence of eIF4AIII19.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Abnormal localization of osk mRNA.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
References (27)