FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\otu19
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General Information
Symbol
Dmel\otu19
Species
D. melanogaster
Name
FlyBase ID
FBal0013366
Feature type
allele
Associated gene
Dmel\otu
Associated Insertion(s)
P{}otu19
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
PM hybrid dysgenesis
Progenitor genotype
Associated Insertion(s)
P{}otu19
Cytology
Description

The P elements in otu18, otu19 and otu21 are inserted at exactly the same base position, between 14 and 15bp upstream of the first major transcription start site, designated as +1 in Comer et al., Gene 118: 171-179. The target site duplication GGCTAGAT, located between -14 and -7 is found at both ends of the insertions. Southern analysis revealed the otu19 P insert to be 2.0kb and in the same transcriptional orientation as the otu gene.

(Sass et al., 1993)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      oncogenic; cystocytes continue dividing and produce tumors

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Mohler.

      Comments
      Comments

      ONC class allele.

      (Sass et al., 1993)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      otu19
      otuP2
      (Sass et al., 1993)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)