FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Pc21
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General Information
Symbol
Dmel\Pc21
Species
D. melanogaster
Name
FlyBase ID
FBal0013571
Feature type
allele
Associated gene
Dmel\Pc
Associated Insertion(s)
Carried in Construct
Also Known As
PcT1
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Tiong and Russell, 1990, Kennison and Tamkun, 1988)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Pc21 Dlw+/Pc+ Dlw1 double heterozygotes have an enhanced ventral to dorsal wing transformation.

      (Tiong et al., 1995)

      Heterozygous adults show transformations of 3rd and 2nd leg to 1st leg, wing to haltere, and ventral wing margin to dorsal wing margin.

      (Tiong and Russell, 1990)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      AntpScx, Pc21 has visible phenotype, suppressible by Nsf2urd-2/urd[+]

      (Kennison and Tamkun, 1988)

      AntpScx, Pc21 has visible phenotype, suppressible by vtd1/vtd[+]

      (Kennison and Tamkun, 1988)
      Other
      Statement
      Reference

      AntpScx, Pc21 has visible phenotype

      (Kennison and Tamkun, 1988)
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      AntpScx, Pc21 has sex comb phenotype, suppressible by Nsf2urd-2/urd[+]

      (Kennison and Tamkun, 1988)

      AntpScx, Pc21 has sex comb phenotype, suppressible by vtd1/vtd[+]

      (Kennison and Tamkun, 1988)
      Other
      Statement
      Reference

      AntpScx, Pc21 has sex comb phenotype

      (Kennison and Tamkun, 1988)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      ScrScx/ScrTpl9 males (in which the haplolethality of the Df(3R)Tpl9 chromosome has been rescued by Dp(3;3)Dfdrv1) also carrying Pc21 have an average of 8.5 ectopic sex comb teeth per second leg and an average of 8.4 ectopic sex comb teeth per third leg.

      (Southworth and Kennison, 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      S. Tiong.

      (Kennison and Tamkun, 1988)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Pc21
      PcT1
      (Tiong et al., 1995, Tiong and Russell, 1990, Kennison and Tamkun, 1988)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)