Open Close
General Information
Symbol
Dmel\red1
Species
D. melanogaster
Name
FlyBase ID
FBal0014517
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

A14300441C

Reported nucleotide change:

A14300442C

Amino acid change:

N90H | red-PF; N90H | red-PB; N90H | red-PG; N90H | red-PC; N67H | red-PA; N67H | red-PD; N67H | red-PE

Reported amino acid change:

N67H

Comment:

The nucleotide position is from chromosome arm 3R (r6). The amino acid position listed is for isoforms PA, PD, and PE. In isoforms PB, PF, and PG, the position is N90H. (Curator note- reported nucleotide position appears to be off by 1).

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: N67H.

Nucleotide substitution: A14300442C.

The nucleotide position is from chromosome arm 3R (r6). The amino acid position listed is for isoforms PA, PD, and PE. In isoforms PB, PF, and PG, the position is N90H.

Carried on aberration
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

red1/Df(3R)Exel6267 and red1/Df(3R)BSC487 flies show both the eye and Malpighian tubule coloration of red1 homozygotes.

Eye colour: dark brown. Malpighian tubule colour: red (larvae and adults).

Pigment of Malpighian tubules are ommochromes.

Eyes contain less drosopterin and isoxanthopterin and more of the other pteridines than normal. Eye color autonomous in red1 eye discs transplanted into wild-type host. Wild-type Malpighian tubes acquire some red pigment after transplantation into red1 hosts.

RK1. Malpighian tubule colour: rusty red. Malpighian tubule colour: colourless, with v1. Malpighian tubule colour: colourless, with cn1. Eye colour: brown, darkening with age.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

red1 has abnormal eye color | recessive phenotype, enhanceable by kar2

Enhancer of
Statement
Reference

red1 is an enhancer of abnormal eye color | recessive phenotype of kar2

Phenotype Manifest In
Enhanced by
Statement
Reference

red1 has pigment cell phenotype, enhanceable by kar2

Enhancer of
Statement
Reference

red1 is an enhancer of pigment cell phenotype of kar2

Additional Comments
Genetic Interactions
Statement
Reference

Eye colour: orange with kar2.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (2)
Stocks (446)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (10)