FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ry516
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General Information
Symbol
Dmel\ry516
Species
D. melanogaster
Name
FlyBase ID
FBal0015012
Feature type
allele
Associated gene
Dmel\ry
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

loss of function allele

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Gray et al., 1991)

loss of function allele

(Lindsley and Zimm, 1992)
Mutagen
ethyl nitrosourea
(Lindsley and Zimm, 1992, Gray et al., 1991, Doerig et al., 1988)
Progenitor genotype
ry+5
(Doerig et al., 1988)
Cytology
Description

C-->T; CAG-->TAG (Gln-->Amber) at +1521.

(Lindsley and Zimm, 1992)

Nucleotide substitution: C1521T (coordinates as in FBrf0046390). This changes a Gln to a stop codon.

(Gray et al., 1991)

Nucleotide substitution: C1522T. This changes a glutamine to an amber stop codon.

(Doerig et al., 1988)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:13,035,688..13,035,688 [+]
Nucleotide change:

C13035688T

Reported nucleotide change:

C1522T

Amino acid change:

Q705term | ry-PA

Reported amino acid change:

Q?term

(Gray et al., 1991, Doerig et al., 1988)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The eyes of male ry516 flies carrying tRNA:Y1:22Faam are changed towards wild-type compared to ry516 females carrying tRNA:Y1:22Faam.

      (Doerig et al., 1988)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      Non-complementing allele.

      (Lindsley and Zimm, 1992)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      McCarron.

      (Lindsley and Zimm, 1992)
      Comments
      Comments

      The eye colour of male ry516 tRNA:Y1:22Faam flies suggests that ry516 is an amber nonsense mutation.

      (Doerig et al., 1988)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ry516
      Name Synonyms
      Secondary FlyBase IDs
        References (4)