FB2026_02 , released June 18, 2026
Allele: Dmel\ry545
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General Information
Symbol
Dmel\ry545
Species
D. melanogaster
Name
FlyBase ID
FBal0015018
Feature type
allele
Associated gene
Dmel\ry
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

loss of function allele

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Gray et al., 1991)

loss of function allele

Mutagen
ethyl nitrosourea
(Gray et al., 1991)
Progenitor genotype
ry+5
(Hilliker et al., 1992, Reaume et al., 1989)
Cytology
Description

Nucleotide substitution: G-551A (coordinates as in FBrf0046390). This prevents splicing.

(Gray et al., 1991)

Point mutation of the 3' acceptor sit eof the 5' intron.

(Reaume et al., 1989)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:13,033,617..13,033,617 [+]
Nucleotide change:

G13033617A

Reported nucleotide change:

G551A

Comment:

Splice acceptor mutation.

(Gray et al., 1991, Lee et al., 1987)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes are hypersensitive to paraquat.

      (Hilliker et al., 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      non-complementing allele

      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      McCarron.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ry545
      Name Synonyms
      Secondary FlyBase IDs
        References (5)