FB2026_02 , released June 18, 2026
Allele: Dmel\ry5205
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General Information
Symbol
Dmel\ry5205
Species
D. melanogaster
Name
FlyBase ID
FBal0015073
Feature type
allele
Associated gene
Dmel\ry
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

Mutagen
ethyl nitrosourea
(Gray et al., 1991, Clark et al., 1986)
Progenitor genotype
ry+5
(Clark et al., 1986)
Cytology
Description

Mutation located in the pterin molybdenum cofactor domain: amino acid substitution G1266D.

(Hughes et al., 1992)

Nucleotide substitution: G3486A (coordinates as in FBrf0046390). This results in the amino acid change: Gly to Asp.

(Gray et al., 1991)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:13,037,653..13,037,653 [+]
Nucleotide change:

G13037653A

Reported nucleotide change:

G3486A

Amino acid change:

G1266D | ry-PA

Reported amino acid change:

G1266D

(Hughes et al., 1992, Gray et al., 1991)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      25% CRM;

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      complementing allele

      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      McCarron.

      Comments
      Comments

      Complements with other ry null alleles.

      (Gray et al., 1991)

      Assayed for xanthine dehydrogenase activity in gel filtered extracts of Drosophila.

      (Hughes et al., 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ry5205
      ryps5205
      (Clark et al., 1986)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)