FB2026_03 , released September 17, 2026
Allele: Dmel\ry5281
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General Information
Symbol
Dmel\ry5281
Species
D. melanogaster
Name
FlyBase ID
FBal0015086
Feature type
allele
Associated gene
Dmel\ry
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

Mutagen
ethyl nitrosourea
(Gray et al., 1991)
Progenitor genotype
Cytology
Description

Amino acid replacement: L127F.

(Doyle et al., 1996)

Amino acid replacement: L127F. Mutation is located in the iron-sulphur domain.

(Hughes et al., 1992)

Nucleotide substitution: C-214T (coordinates as in FBrf0046390). This results in the amino acid change: Leu to Phe.

(Gray et al., 1991)

C --> T at -214; CTT-->TTT (Leu-->Phe)

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:13,033,954..13,033,954 [+]
Nucleotide change:

C13033954T

Reported nucleotide change:

C214T

Amino acid change:

L127F | ry-PA

Reported amino acid change:

L127F

(Hughes et al., 1992, Gray et al., 1991)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      50% CRM

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      McCarron.

      Comments
      Comments

      Assayed for xanthine dehydrogenase activity in gel filtered extracts of Drosophila.

      (Hughes et al., 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ry5281
      Name Synonyms
      Secondary FlyBase IDs
        References (4)