FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\sca2
Open Close
General Information
Symbol
Dmel\sca2
Species
D. melanogaster
Name
FlyBase ID
FBal0015255
Feature type
allele
Associated gene
Dmel\sca
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
(Ives, 1967)
Progenitor genotype
Cytology
Description

Breakpoint in intron III and an insertion of unknown DNA causing truncation of the protein after Lys460 (absence of carboxy terminal sequences).

(Hu et al., 1995)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
sequence_alteration
2R:12,799,791..12,799,991 [+]
Comment:

A rearrangement with unknown DNA inserted into intron 3 causing truncation of the protein after K460.

(Hu et al., 1995)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes exhibit rough eyes and twinned bristles.

      (Rabinow and Birchler, 1990)

      no reduction in bristle number

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (1)
      Stocks (1)
      Kyoto
      107553
      sca2
      Notes on Origin
      Discoverer

      Ives, 31st Dec. 1965.

      Ives.

      (Ives, 1967)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      sca2
      (Cook and Cook, 2010.5.7, Christensen et al., 2008.4.15)
      sca65131
      (Ives, 1967)
      sca65l31
      scaG5131
      (Verheyen et al., 1996)
      scaG5l31
      (Verheyen et al., 1996)
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0046406
      References (7)