FB2026_02 , released June 18, 2026
Allele: Dmel\Scr11
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General Information
Symbol
Dmel\Scr11
Species
D. melanogaster
Name
FlyBase ID
FBal0015287
Feature type
allele
Associated gene
Dmel\Scr
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

loss of function allele

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Sivanantharajah and Percival-Smith, 2009)

loss of function allele

(Pattatucci et al., 1991)
Mutagen
ethyl methanesulfonate
(Pattatucci et al., 1991)
Progenitor genotype
Cytology

Polytene chromosomes normal.

(Pattatucci et al., 1991)
Description

Nucleotide substitution: G1112A.

(Sivanantharajah and Percival-Smith, 2009)

Amino acid replacement: W371term.

(Sivanantharajah and Percival-Smith, 2009)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:6,825,524..6,825,524 [-]
Nucleotide change:

G6825524A

Reported nucleotide change:

G1112A

Amino acid change:

W371term | Scr-PA; W371term | Scr-PB; W371term | Scr-PD; W371term | Scr-PE; W371term | Scr-PF

Reported amino acid change:

W371term

(Sivanantharajah and Percival-Smith, 2009)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The head structures are severely disrupted in first instar homozygous larvae and the number of rows of T1 beard denticles is reduced.

      Heterozygous males have a reduction in the number of sex comb bristles on the prothoracic leg compared to wild-type males.

      (Sivanantharajah and Percival-Smith, 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Lambert.

      (Lindsley and Zimm, 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Scr11
      (Becker et al., 2016, Sivanantharajah and Percival-Smith, 2009)
      Scrc12
      (Pattatucci et al., 1991)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)