FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ScrE2
Open Close
General Information
Symbol
Dmel\ScrE2
Species
D. melanogaster
Name
FlyBase ID
FBal0015309
Feature type
allele
Associated gene
Dmel\Scr
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Kennison and Tamkun, 1988)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      ScrE2/+ males (ScrE2 chromosome carries the "E2" mutation in cis to ScrScx) have an average of 0.8 ectopic sex comb teeth per second leg and have no ectopic sex comb teeth on the third legs. ScrE2/Scr4 ; Dp(3;Y)77ab males (ScrE2 chromosome carries the "E2" mutation in cis to ScrScx) have an average of 0.02 ectopic sex comb teeth per second leg and have no ectopic sex comb teeth on the third legs.

      (Southworth and Kennison, 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      ScrE2 is a suppressor of phenotype of AntpScx

      (Kennison and Tamkun, 1988)

      ScrE2 is a suppressor of phenotype of Pc4

      (Kennison and Tamkun, 1988)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Suppresses the extra sex comb phenotype of AntpScx/Df(3R)Antp17; Dp(3;Y)Antp+. Causes between 50% and 100% suppression of the Pc4/+ extra sex combs phenotype.

      (Kennison and Tamkun, 1988)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Induced on: AntpScx.

      (Kennison and Tamkun, 1988)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ScrE2
      Name Synonyms
      Secondary FlyBase IDs
        References (2)