FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\sd10
Open Close
General Information
Symbol
Dmel\sd10
Species
D. melanogaster
Name
FlyBase ID
FBal0015356
Feature type
allele
Associated gene
Dmel\sd
Associated Insertion(s)
Carried in Construct
Also Known As
sd11L
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Katzen and Bishop, 1996, Katzen, 1990)
Progenitor genotype
Cytology
Description

Amino acid replacement: H433L.

(Srivastava et al., 2004)

The coordinates given for the mutant lesion refer to the sd E21 isoform. The protein encoded by the sd E7 isoform appears to be unaffected in this mutant.

(Srivastava et al., 2004)

Nucleotide substitution: A?T.

(Srivastava et al., 2004)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
X:15,824,423..15,824,423 [+]
Nucleotide change:

A15824423T

Reported nucleotide change:

A?T

Amino acid change:

H363L | sd-PA; H433L | sd-PB; H363L | sd-PC; H403L | sd-PD; H433L | sd-PE; H433L | sd-PF; H433L | sd-PG; H428L | sd-PH; H428L | sd-PI; H403L | sd-PJ; H433L | sd-PK; H363L | sd-PL; H428L | sd-PM; H363L | sd-PN; H403L | sd-PO; H403L | sd-PP; H618L | sd-PQ; H433L | sd-PR; H433L | sd-PS; H368L | sd-PT; H403L | sd-PU; H428L | sd-PV

Reported amino acid change:

H433L

(Srivastava et al., 2004)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      sd10/sdETX4 flies have wild-type wings.

      (Srivastava et al., 2004)

      At the late lethal stage individuals exhibit normal wings and gross morphological head abnormalities.

      (Campbell et al., 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Complements

      sdETX4

      (Srivastava et al., 2004)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      em11
      (Katzen and Bishop, 1996)
      sd10
      sd11L
      (Caine et al., 2014, Srivastava et al., 2004, Campbell et al., 1991)
      sdEM11
      (Katzen, 1990)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)