FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\SdhA8
Open Close
General Information
Symbol
Dmel\SdhA8
Species
D. melanogaster
Name
FlyBase ID
FBal0015386
Feature type
allele
Associated gene
Dmel\SdhA
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

heat sensitive loss of function allele

heat sensitive amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

heat sensitive amorphic allele - molecular evidence

(Lawrence, 1981)

heat sensitive loss of function allele

(Lawrence, 1981)
Mutagen
ethyl methanesulfonate
(Lindsley and Zimm, 1992, Lawrence, 1981)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Lethal at 25oC viable at 18oC.

      (Lindsley and Zimm, 1992)

      Homozygous flies are fully viable at 18[o]C (females are fertile, but males are virtually sterile at 17-18[o]C), but when transferred to 25[o]C, adults slowly sicken and die after about a week.

      (Lawrence, 1981)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Lawrence.

      (Lindsley and Zimm, 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Sdh8
      SdhA8
      sdh8
      (Lawrence, 1981)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)