FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\shakB24
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General Information
Symbol
Dmel\shakB24
Species
D. melanogaster
Name
FlyBase ID
FBal0015597
Feature type
allele
Associated gene
Dmel\shakB
Associated Insertion(s)
Carried in Construct
Also Known As
EF535
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Krishnan et al., 1995)
Progenitor genotype
Cytology
Description

17bp deletion in the lethal specific exons that removes the initiation site and the first two codons.

(Krishnan et al., 1995)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
X:20,784,622..20,784,638 [-]
Comment:

17bp deletion in the lethal-specific exons that removes the initiation site and the first two codons.

(Krishnan et al., 1995)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      DLMs and TTMs respond normally to brain shocks.

      (Krishnan et al., 1995)

      Abnormal electrophysiological phenotype. Homozygous flies exhibit uncoordinated leg movements under ether anaesthesia and do not jump to a light off stimulus. Heterozygotes are fully viable and exhibit no neuronal defects.

      (Baird et al., 1990)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      Complements shakB3.

      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Lefevre.

      Comments
      Comments

      shakB alleles exhibit a complex pattern of complementation.

      (Baird et al., 1990)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      EF535
      (Krishnan et al., 1995, Balakrishnan and Rodrigues, 1991)
      PasEF535
      (Baird et al., 1990)
      l(1)EF535
      shakB24
      shakBEF535
      (Perrimon et al., 1989)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)