FB2026_02 , released June 18, 2026
Allele: Dmel\shi3
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General Information
Symbol
Dmel\shi3
Species
D. melanogaster
Name
FlyBase ID
FBal0015612
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
shits3
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
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Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Mutants are shifted to 29oC at the time of microchaetae precursor determination (14-10 hours APF). Mutants differentiate a large number of extra microchaetes, phenotype is more severe in medial than lateral areas of the thorax. The mutant phenotype results from the development of an excess of neural precursors at the expense of epidermal cells. Clones generated during the first and second larval stages present a strong neurogenic phenotype and bristles along the border can be either wild type or mutant. Occasionally a mutant bristle can be found adjacent to a wild type one. Mutant cells are defective in both sending and receiving the lateral signal.

temperature-sensitive temperature of adult paralysis: 29oC temperature of larval paralysis: 29oC temperature causing developmental defects: 29oC viability of allele over deficiency: very weak

External Data
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Phenotypic Class
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Xenogenetic Interactions
Statement
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Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Grigliatti.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (4)