FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ssa40a
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General Information
Symbol
Dmel\ssa40a
Species
D. melanogaster
Name
FlyBase ID
FBal0016093
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The courtship index of naive ssa40a males is lower than that of CantonS controls.

Mutant males show can form immediate memory in a courtship suppression paradigm (CCSP), with the courtship index being reduced immediately after conditioning, but have a significant reduction in the learning index one day after training compared to immediately after training, indicating a defect in long-term memory.

Segmentation of hemizygotes is temperature sensitive. Hemizygotes exhibit incomplete tarsal segmentation.

Homozygotes and ssa40a/ssaP88 flies show transformation of the arista to distal mesothoracic tarsus. Expressivity of the phenotype is higher in ssa40a/ssaP88 flies than in ssa40a homozygotes. The expressivity of the phenotype decreases with increasing temperature in ssaB/ssa40a flies. A high proportion of homozygous or ssa40a/ssaP88 flies produce an ectopic tarsal response to chemical stimulation at 25oC. Homozygous and ssa40a/ssaP88 flies can often fly.

cold-sensitive phenotype normal in flies raised at 29oC; fully penetrant at 17oC <up>mean number of tarsal segments = 2.8; incidence of tarsal claws = 1.3% as recorded by Garcia-Bellido (1968) probably in flies raised at 25oC</up>. Phenocritical stage in first half of third instar (Grigliatti and Suzuki, 1971). Shifts from 17oC to 29oC early in third instar restrict transformation to base of arista; distal extent of transformation increases as shift is effected later in development (Grigliatti and Suzuki). Opposite response to temperature for antennal transformation but not tarsal fusion reported by Mglinetz (1977). Developmental compartments demonstrated in antennal legs (Morata and Lawrence, 1979). cold-sensitive

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Other
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference

ssa40a has phenotype, enhanceable by al1

Enhancer of
Statement
Reference

ssa40a is an enhancer of phenotype of al1

Other
Additional Comments
Genetic Interactions
Statement
Reference

al1 ssa40a flies exhibit partial transformation of third antennal segment to basitarsus; anomalous outgrowths of distal basitarsus and foreshortening of second and third tarsal joints of thoracic legs; ss phenotype also enhanced.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer

Buzzati-Traverso, 2nd Jan. 1940.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (14)