FB2026_03 , released September 17, 2026
Allele: Dmel\su(msm1)1
Open Close
General Information
Symbol
Dmel\su(msm1)1
Species
D. melanogaster
Name
FlyBase ID
FBal0016327
Feature type
allele
Associated gene
su(msm1)
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Has no effect on fertility by itself.

      (Nishida, 1980)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      su(msm1)1 is a suppressor of male sterile | recessive phenotype of ms(3)HO5A1

      (Nishida, 1980)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      su(msm1)1 is a suppressor of testis phenotype of ms(3)HO5A1

      (Nishida, 1980)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Partly suppresses the ms(3)HO5A1 rudimentary testis phenotype, allowing spermatogenesis to proceed to a more advanced stage; males homozygous for both ms(3)HO5A1 and su(msm1)1 have spiral shaped testes, but these testes are considerably shorter and thinner than those of normal males. Elongated spermatid bundles are seen in these testes. The suppression is incomplete, as 8% of su(msm1)1 ms(3)HO5A1 double homozygous males have rudimentary testes. 7% of su(msm1)1 ms(3)HO5A1 double homozygous males are fertile, suggesting either that the ms(3)HO5A1 allele is leaky, or partial dominance of su(msm1)1 over its wild-type allele.

      (Nishida, 1980)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      su(m15A)
      (Nishida, 1980)
      su(msm1)1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)