FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\tlla
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General Information
Symbol
Dmel\tlla
Species
D. melanogaster
Name
FlyBase ID
FBal0016891
Feature type
allele
Associated gene
Dmel\tll
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Strecker et al., 1988)
Mutagen
X ray
(Strecker et al., 1988, Strecker et al., 1986)
Progenitor genotype
Cytology

Polytene chromosomes normal.

(Strecker et al., 1988, Strecker et al., 1986)
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Anteriorly embryos have a continuous dorsal bridge and reduced dorsal appendages, posteriorly embryos are indistinguishable tll1 embryos. Slight reduction in brain region. Small increase in segment length.

      (Strecker et al., 1988)

      tlla/tll1 embryos have shortened pharyngeal ridges. A8 and the telson are missing. tlla homozygous embryos consistently have a reduced number of segmented ganglia.

      (Strecker et al., 1986)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      tlll49/tlla is rescued by tll+t10.2

      (Pignoni et al., 1990)
      Comments

      Mutant phenotype can be rescued to adulthood by P element mediated transformation of the wild type tll gene copy.

      (Pignoni et al., 1990)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      tlla
      Name Synonyms
      Secondary FlyBase IDs
        References (3)