FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\uex4
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General Information
Symbol
Dmel\uex4
Species
D. melanogaster
Name
FlyBase ID
FBal0017576
Feature type
allele
Associated gene
Dmel\uex
Associated Insertion(s)
Carried in Construct
Also Known As
EMS45-17
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Hilliker, 1976)
Progenitor genotype
Cytology
Description

Point mutation.

(Hilliker, 1976)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Most uex2/uex4 and uex4/Df(2R)247 animals die in the pupal stage or during eclosion. Rare uex4/Df(2R)247 adult escapers exhibit smaller body size, misshapen hind legs and unextended wings within incomplete penetrance - escapers show any combination of these phenotypes and sometimes appear fully wild type.

      Most uex4/Df(2R)M41A10 animals die in the pupal stage or during eclosion, with escapers having unextended wings.

      uex4/Df(2R)34-2 animals are largely viable with wild type legs and wings.

      uex4/uexL2 animals are largely viable with wild type legs and wings, though significant pupal lethality is seen.

      (Coulthard et al., 2010)

      Rare hemizygous survivors may have etched tergites and small bodies.

      (Lindsley and Zimm, 1992)

      Hemizygotes are pupal lethal. Adult escapers have unexpanded wings, misshapen third legs, etched tergites and a small body size.

      (Hilliker, 1976)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      EMS 45-17
      (Coulthard et al., 2010)
      EMS45-17
      (Dimitri, 1991, Hilliker, 1976)
      l(2)EMS45-17
      (Lindsley and Zimm, 1992)
      uex45-17
      (Coulthard et al., 2010)
      uex4
      (Coulthard et al., 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)