FB2026_02 , released June 18, 2026
Allele: Dmel\wco2
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General Information
Symbol
Dmel\wco2
Species
D. melanogaster
Name
FlyBase ID
FBal0018226
Feature type
allele
Associated gene
Dmel\w
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Farmer, 1974)
Progenitor genotype
Cytology
Description

Amino acid relacement: G588S. Nucleotide substitution: A5311G.

(Ewart et al., 1994)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
X:2,791,031..2,791,031 [-]
Nucleotide change:

G2791031A

Reported nucleotide change:

A5311G

Amino acid change:

G588S | w-PA

Reported amino acid change:

G588S

(Ewart et al., 1994)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eye colour: wild-type, with bw+.

      (Ewart et al., 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      bw6, wco2 has visible | recessive phenotype

      (Ewart et al., 1994)

      bw6, wco2 has abnormal eye color phenotype

      (Ewart et al., 1994)

      bwT50, wco2 has visible phenotype

      (Ewart et al., 1994)
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      wco2 has phenotype, suppressible by bw6

      (Farmer, 1974)
      Other
      Statement
      Reference

      bw6, wco2 has pigment cell phenotype

      (Ewart et al., 1994)

      bwT50, wco2 has eye phenotype

      (Ewart et al., 1994)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Eye colour: brown, with bw6. Almost complete absence of red pteridine pigments with bw6.

      (Ewart et al., 1994)

      Eye colour: brown, with bw6.

      (Farmer, 1974)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Farmer.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      wco2
      wcoJ
      (Farmer, 1974)
      Name Synonyms
      white-coral J
      (Farmer, 1974)
      Secondary FlyBase IDs
        References (5)