FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\yhd8
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General Information
Symbol
Dmel\yhd8
Species
D. melanogaster
Name
hybrid dysgenesis 8
FlyBase ID
FBal0018683
Feature type
allele
Associated gene
Dmel\y
Associated Insertion(s)
P{}yhd8
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
PM hybrid dysgenesis
(Chia et al., 1986)
Progenitor genotype
Associated Insertion(s)
P{}yhd8
Cytology
Description

Insertion probably lies within the 5' transcribed but non-translated leader. Insertion has no 8bp target site duplication but is flanked by a 5bp deletion corresponding to nucleotides +15 to +20. The P-element 31bp inverted terminal repeats are conserved.

(Howes et al., 1988)

1.2kb insertion within a 197bp fragment located between a BamHI site at coordinate 3.0 and a BalI site 197bp to its left (coordinates relative to molecular map in this reference).

(Chia et al., 1986)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
X07529
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Body colour: abolishes pigment in all larval and adult cuticular structures. Type 1 allele.

      (Howes et al., 1988)

      Body colour: type 1 mutant - total loss of pigmentation from all cuticle structures.

      (Chia et al., 1986)

      Body colour: yellow; hairs & bristles brown with yellow tips; wing veins, wing hairs, yellow.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Chia.

      Comments
      Comments

      Precise excision of the P-element restores the wild-type phenotype.

      (Chia et al., 1986)
      External Crossreferences and Linkouts ( 1 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      yhd8
      Name Synonyms
      hybrid dysgenesis 8
      Secondary FlyBase IDs
        References (3)