FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\zen4
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General Information
Symbol
Dmel\zen4
Species
D. melanogaster
Name
FlyBase ID
FBal0018858
Feature type
allele
Associated gene
Dmel\zen
Associated Insertion(s)
Carried in Construct
Also Known As
zenf62
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Ferguson and Anderson, 1992)
Mutagen
ethyl methanesulfonate
Progenitor genotype
Cytology

Polytene chromosomes normal.

Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In mutant embryos, the dorsal medial head epidermis fails to develop as reflected by the presence of a continuous optic placode across the dorsal midline.

      (Chang et al., 2003)

      Embryos are ventralised.

      (Ferguson and Anderson, 1992)

      zen4/Df(3R)Scr embryos show a similar pattern of defects as zen7/Df(3R)Scr embryos. The optic lobe is absent.

      (Wakimoto et al., 1984)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Mutant phenotype is suppressed by increasing the dpp+ gene dosage.

      (Ferguson and Anderson, 1992)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      Fornili.

      Comments
      Comments

      Moderate zen allele.

      (Ferguson and Anderson, 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      zen4
      zenf62
      (Yip et al., 1997, Ferguson and Anderson, 1992, Strecker et al., 1992, Wakimoto et al., 1984)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)