FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\wgCE7
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General Information
Symbol
Dmel\wgCE7
Species
D. melanogaster
Name
FlyBase ID
FBal0027936
Feature type
allele
Associated gene
Dmel\wg
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

Mutagen
    Nature of the Allele
    Allele class

    amorphic allele - genetic evidence

    (Ranganayakulu et al., 1996)
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Nucleotide substitution at the 3' end of the fourth intron changing the splice acceptor site for exon 5 from AG to AA, resulting in failure to splice out the fourth intron. The first three nucleotides of the intron encode a stop codon truncating the protein at the end of the fourth exon.

    (Bejsovec and Wieschaus, 1995)

    wgCE7 encodes an identical product to wgS84 (Bejsovec and Wieschaus).

    (Couso and Martinez Arias, 1994)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    2L:7,314,879..7,314,879 [+]
    Nucleotide change:

    G7314879A

    Reported nucleotide change:

    G?A

    Comment:

    Nucleotide substitution at the 3' end of the fourth intron changing the splice acceptor site for exon 5 from AG to AA, resulting in failure to splice out the fourth intron. The first three nucleotides of the intron encode a stop codon truncating the protein at the end of the fourth exon.

    (Bejsovec and Wieschaus, 1995)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        panS28/+, wgCE7/+ flies show phenotypes characteristic of reduced wg activity.

        (Brunner et al., 1997)

        wgCE7/wgl-16 transheterozygotes are pupal lethal. Lethality can be suppressed by wgPE1.

        (Bejsovec and Wieschaus, 1995)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        wgCE7
        (Mariappa et al., 2011)
        Name Synonyms
        Secondary FlyBase IDs
          References (8)