FlyBase Allele Report: Dmel\bob[1]

General Information

Symbol

Dmel\bob¹

Species

D. melanogaster

Name

FlyBase ID

FBal0027978

Feature type

allele

Associated gene

bob

Associated Insertion(s)

P{PZ}bob¹

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Castrillon et al., 1993)

Progenitor genotype

Associated Insertion(s)

P{PZ}bob¹

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{PZ}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:4,803,476..4,803,476 [+]

(Morris et al., 2003, Spradling et al., 1999, BDGP Project Members, 1994-1999, Castrillon et al., 1993)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal meiotic cell cycle

(Castrillon et al., 1993)

female fertile (with bob^8-37)

(Morris et al., 2003)

female fertile (with bob^38-2)

(Morris et al., 2003)

female fertile (with bob^43-21)

(Morris et al., 2003)

female fertile (with bob^C871)

(Morris et al., 2003)

male fertile (with bob^8-37)

(Morris et al., 2003)

male fertile (with bob^38-2)

(Morris et al., 2003)

male fertile (with bob^43-21)

(Morris et al., 2003)

male fertile (with bob^C871)

(Morris et al., 2003)

male sterile | recessive

(Spradling et al., 1999)

partially lethal - majority die | recessive

(Castrillon et al., 1993)

viable (with bob^8-37)

(Morris et al., 2003)

viable (with bob^38-2)

(Morris et al., 2003)

viable (with bob^43-21)

(Morris et al., 2003)

Phenotype Manifest In

Nebenkern

(Castrillon et al., 1993)

Detailed Description

Statement

Reference

A few spermatid per cyst have nuclei or nebenkern of abnormal size.

(Castrillon et al., 1993)

A few spermatids per cyst have nuclei or Nebenkern of abnormal size.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

101718

P{PZ}bob¹ ry⁵⁰⁶ / TM3, ry^RK Sb¹

Notes on Origin

Discoverer

A. Spradling.

Comments

The bob¹ allele in the Bloomington Stock collection may have lost the original P-insertion, since it is no longer male or female sterile in trans to bob^C871, bob^8-37, bob^38-2 or bob^43-21.

(Morris et al., 2003)

Complements: shk¹.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

bob⁰⁶²⁰⁸

bob¹

ms(3)06208

(Spradling et al., 1999)

ms(3)06208⁰⁶²⁰⁸

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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