FlyBase Allele Report: Dmel\bt[l-a]

General Information

Symbol

Dmel\bt^l-a

Species

D. melanogaster

Name

FlyBase ID

FBal0027983

Feature type

allele

Associated gene

Dmel\bt

Associated Insertion(s)

?{}bt^l-a

Carried in Construct

Also Known As

2^a

Key Links

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

X ray

(Hochman, 1971, Hochman et al., 1964)

Progenitor genotype

Associated Insertion(s)

?{}bt^l-a

Cytology

Description

141bp insertion in the core region of bt.

(Ayme-Southgate et al., 1995)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal

(Hochman, 1971)

lethal | recessive

(Hochman et al., 1964)

lethal - all die during embryonic stage (with bt^D)

(Ayme-Southgate et al., 1995)

lethal - all die during embryonic stage | recessive

(Ayme-Southgate et al., 1995)

some die during embryonic stage (with bt^D)

(Ayme-Southgate et al., 1995)

some die during embryonic stage | recessive

(Ayme-Southgate et al., 1995)

Phenotype Manifest In

Detailed Description

Statement

Reference

Homozygotes die as late embryos and do not have spontaneous muscle contractions. bt^D/bt^l-a transheterozygotes die as embryos.

(Ayme-Southgate et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

bt^D

(Ayme-Southgate et al., 1995)

bt^l-k

(Ayme-Southgate et al., 1995)

bt^l-f

(Ayme-Southgate et al., 1995)

bt^l-b

(Ayme-Southgate et al., 1995)

Comments

Non-complementing allele.

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

(Hochman et al., 1964)

2^a

(Hochman, 1976, Hochman, 1974, Hochman, 1971)

bt^l-a

l(4)2^a

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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