FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\D5
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General Information
Symbol
Dmel\D5
Species
D. melanogaster
Name
FlyBase ID
FBal0029146
Feature type
allele
Associated gene
Dmel\D
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Russell et al., 1996, Carpenter, 1994)
Progenitor genotype
Caused by aberration
Df(3L)D5
Cytology
Description

The aberration breakpoint is +2 to +4 kb 5' of the D transcription unit (where 0 indicates the translation start site).

(Sanchez Soriano and Russell, 2000)

Distal breakpoint maps approximately 4-5kb 5' to the D transcription unit.

(Russell et al., 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In heterozygotes, the alar lobe is affected and weak anterior effects are seen on the medial costa and the radius.

      (Russell, 2000)

      Exhibits a dominant wing hinge phenotype.

      (Sanchez Soriano and Russell, 2000)

      Homozygous viable. Heterozygotes have wings held out at 90o, they are often curved down and more narrow than wild type. Alulae are shortened from proximal end, the remnant is a delta-shaped flap with marginal bristles. The halteres are fully down, the abdomen is narrow and has normal bristles. Viable over all deficiencies in the 70CD region as well as all other D alleles and Dr8. D5/+; eyD/+ flies are viable, unlike dominant late pupal lethal interaction of D1 with eyD. Viable when heterozygous with all lethal D alleles, the phenotype is the sum of the two D alleles.

      (Carpenter, 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      A.T.C. Carpenter.

      (Carpenter, 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      D5
      Name Synonyms
      Secondary FlyBase IDs
        References (4)