FB2026_02 , released June 18, 2026
Allele: Dmel\Deltasup4
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General Information
Symbol
Dmel\Deltasup4
Species
D. melanogaster
Name
FlyBase ID
FBal0029367
Feature type
allele
Associated gene
Dmel\Delta
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Mutation is within the 9th EGF-like repeat in the Dl extracellular domain.

    (Lieber et al., 1992)

    Amino acid replacement: G520R.

    (Lieber et al., 1992)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    3R:19,305,772..19,305,772 [-]
    Nucleotide change:

    G19305772A

    Amino acid change:

    G520R | Delta-PA; G520R | Delta-PB; G520R | Delta-PC

    Reported amino acid change:

    G520R

    (Lieber et al., 1992)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Very reduced viability when heterozygous with Df(3R)Dl-FX3, DlKX1 or DlFE27. Adult escapers have a severe Dl wing phenotype, roughening of compound eye and increase in number of sensory bristles on the notum.

        (Brand and Campos-Ortega, 1990)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Suppressor of
        Statement
        Reference

        Deltasup4 is a suppressor of phenotype of Nspl-1

        (Lieber et al., 1992)
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer

        Selected as: Modifier of Notch "split" alleles.

        (Brand and Campos-Ortega, 1990)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        Deltasup4
        DlSUP4
        Dlsup4
        Name Synonyms
        Secondary FlyBase IDs
          References (2)