FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Gpdh1MB5
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General Information
Symbol
Dmel\Gpdh1MB5
Species
D. melanogaster
Name
FlyBase ID
FBal0029813
Feature type
allele
Associated gene
Dmel\Gpdh1
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
natural population
(Gibson et al., 1991)
Progenitor genotype
Cytology
Description

76bp deletion in the 5' region removing the TATA box and an insertion of 20bp replacing the deleted segment.

(Reed and Gibson, 1994)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
2L:5,943,877..5,943,954 [+]
Comment:

78 bp region deleted and replaced by 20bp insertion in mutant.

Inserted_sequence:

ATTATCCTTATTTCATCATG

(Reed and Gibson, 1994)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
X61224
CAA43536
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Homozygous GpdhMB5 flies and GpdhMB5/Df(2L)GpdhA flies have reduced Gpdh enzyme activity compared to wild-type. Fast electrophoretic variant.

    (Gibson et al., 1991)
    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer

    Isolated from: Mission Beach, Queensland, Australia population, 1986.

    (Gibson et al., 1991)
    External Crossreferences and Linkouts ( 3 )
    Crossreferences
    GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
    GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
    UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    Gpdh1MB5
    GpdhAMB5
    (Reed and Gibson, 1994)
    GpdhMB5
    Name Synonyms
    Secondary FlyBase IDs
      References (2)