The ocellar nerve frequently does not form in LanA mutants. Projections of the ocellar pioneer axons are aberrant. They may fail to grow as far as in wild type, or may extend away from the brain. Sometimes the characteristic pair of ocellar pioneer axon bundles do not form. Instead multiple fascicles form, some of which enter the brain at abnormal positions. Normal or increased levels of ECM surround many structures, including the wing disc and optic stalk. However the ECM in the eye-antenna disc region is reduced. Ocellar pathfinding defects are common. In the extreme case the axons do not leave the epidermis, but extend a short distance within the epidermis. Large bundles of ocellar pioneer axons may abnormally join the fascicles of the ocellar and orbital bristles. These axons eventually stall before reaching the brain. Adult ocellar photoreceptors are born on schedule. Around 50% of LanA mutants show major axon pathfinding defects in the photoreceptor axons of the compound eye. These defects can be detected as early as the 3rd larval instar. The optic stalk is often broad in shape and the axons have a loose and disorganized appearance. The optic nerve is usually split into two or more bundles. Retinal axons form whirls within the retina. Growth cones within the retina extend in abnormal directions and fail to enter the optic stalk. Glial cells are abnormally distributed in the eye.

Embryos, which are morphologically normal (with respect to CNS, PNS, motoneurons, muscles, head, mouthparts and denticle bands) and mobile nevertheless fail to hatch.

LanA[+]/LanA^6-36 is an enhancer of visible | dominant phenotype of sog^EP7

LanA[+]/LanA^6-36 is an enhancer of visible | dominant phenotype of sog^EP11

LanA[+]/LanA^6-36 is an enhancer of wing vein phenotype of sog^EP7

LanA[+]/LanA^6-36 is an enhancer of wing vein phenotype of sog^EP11