FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Polr2BZ45
Open Close
General Information
Symbol
Dmel\Polr2BZ45
Species
D. melanogaster
Name
FlyBase ID
FBal0030143
Feature type
allele
Associated gene
Dmel\Polr2B
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Chen et al., 1993, Mortin et al., 1992)
Progenitor genotype
Cytology
Description

Amino acid replacement: S1098F. Nucleotide substitution: C4211T.

(Chen et al., 1993)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:14,129,500..14,129,500 [+]
Nucleotide change:

C14129500T

Reported nucleotide change:

C4211T|FBrf0059056

Amino acid change:

S1098F | Polr2B-PA; S1098F | Polr2B-PB

Reported amino acid change:

S1098F|FBrf0059056

(Chen et al., 1993)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Exhibits the Ubx effect: heterozygotes partially transform the capitellum of the haltere into the wing blade.

      (Chen et al., 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Polr2BZ45 is an enhancer of visible phenotype of Scer\GAL4ey.PH, brmK804R.UAS.Tag:HA

      (Armstrong et al., 2005)
      NOT Enhancer of
      Statement
      Reference

      Polr2BZ45 is a non-enhancer of visible phenotype of IswiK159R.UAS.Tag:HA, Scer\GAL4ey.PH

      (Armstrong et al., 2005)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Polr2BZ45 is an enhancer of eye phenotype of Scer\GAL4ey.PH, brmK804R.UAS.Tag:HA

      (Armstrong et al., 2005)
      NOT Enhancer of
      Statement
      Reference

      Polr2BZ45 is a non-enhancer of eye phenotype of IswiK159R.UAS.Tag:HA, Scer\GAL4ey.PH

      (Armstrong et al., 2005)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Polr2BZ45
      RpII140Z45
      Z45
      (Chen et al., 1993)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)