FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ScrCP1
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General Information
Symbol
Dmel\ScrCP1
Species
D. melanogaster
Name
FlyBase ID
FBal0030205
Feature type
allele
Associated gene
Dmel\Scr
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Caused by aberration
    Df(3R)CP1
    Cytology
    Description

    Deficiency breakpoint within the Scr transcription unit. The deficiency removes a 3' portion of the Scr transcription unit, leaving the 5' portion and promoter sequences intact.

    (Southworth and Kennison, 2002)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 1 )
        Disease
        Interaction
        References
        ameliorates  Huntington's disease
        modeled by Hsap\HTTQ138.UAS.mRFP1
        (Weiss et al., 2012)
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Heterozygous males have a reduced number of sex comb teeth (4-6) on the first leg. ScrCP1/ScrWrv4 males have no sex comb teeth on the first leg.

        (Southworth and Kennison, 2002)

        Thoracic segment 1 is transformed to thoracic segment 2 and labial is transformed to maxillary.

        (Jack et al., 1988)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        Statement
        Reference

        Scr[+]/ScrCP1 is a suppressor | partially of lethal | pharate adult stage phenotype of Hsap\HTTQ138.UAS.mRFP1, Scer\GAL4elav-C155

        (Weiss et al., 2012)
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference

        One copy of ScrCP1 partially rescues the lethality seen when Hsap\HTTQ138.Scer\UAS.T:Disc\RFP-mRFP is expressed under the control of Scer\GAL4elav-C155 using the P{UAS-HTT.Q138.mRFP}A insertion line.

        (Weiss et al., 2012)
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        ScrCP1
        (Weiss et al., 2012)
        Name Synonyms
        Secondary FlyBase IDs
          References (3)