FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\bossHSB
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General Information
Symbol
Dmel\bossHSB
Species
D. melanogaster
Name
FlyBase ID
FBal0030637
Feature type
allele
Associated gene
Dmel\boss
Associated Insertion(s)
P{hsp70-boss}HSB
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(van Vactor et al., 1991)
Progenitor genotype
Associated Insertion(s)
P{hsp70-boss}HSB
Cytology
Description

The coding region of boss is as for bosshs.P, but expression is differently regulated due to genomic cis-acting sequences outside the P element insertion.

(van Vactor et al., 1991)
Allele components
Component
Use(s)
Inserted element
P{hsp70-boss}
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ubiquitous expression of bossHSB results in the development of multiple R7 photoreceptor cells. These ectopic R7 cells are not produced by bossHSB in a sev14 background.

      (Zipursky et al., 1992)

      boss is strongly expressed on the apical membranes of all cells anterior and posterior to the morphogenetic furrow: all sev-expressing cells have access to the boss inductive cue. Ectopic expression of bossHSB causes the production of extra R7 cells. Double mutant sev14; bossHSB adult eye completely lacks R7 cells.

      (van Vactor et al., 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Expression of boss is heat shock independent, due to proximity of an enhancer element in region flanking the P insertion that promotes widespread transcription of boss cDNA.

      (van Vactor et al., 1991)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      bossHSB
      Name Synonyms
      Secondary FlyBase IDs
        References (2)