FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\comm3
Open Close
General Information
Symbol
Dmel\comm3
Species
D. melanogaster
Name
FlyBase ID
FBal0030918
Feature type
allele
Associated gene
Dmel\comm
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Tear et al., 1996)
Mutagen
X ray
(Tear et al., 1996, Seeger et al., 1993)
Progenitor genotype
Caused by aberration
Tp(3;3)comm3
Cytology
Description

Break at 71E3-5 maps to a PstI-SalI fragment within the 9.6kb EcoRI fragment that includes the comm transcription unit.

(Tear et al., 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Both pairs of commissures are missing in all thoracic and abdominal segments. Many commissural growth cones initially extend toward the midline; however they soon retract and join longitudinal pathways without crossing the midline.

      (Tear et al., 1996)

      Commissural axon pathways in the embryonic ventral nerve cord absent.

      (Seeger et al., 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      comm3
      commX3
      commx3
      Name Synonyms
      Secondary FlyBase IDs
        References (2)