FlyBase Allele Report: Dmel\cpo[l1]

General Information

Symbol

Dmel\cpo^l1

Species

D. melanogaster

Name

FlyBase ID

FBal0030937

Feature type

allele

Associated gene

Dmel\cpo

Associated Insertion(s)

P{lacZ}cpo^l1

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Fernandez-Funez et al., 2000, Bellen et al., 1992)

Progenitor genotype

Associated Insertion(s)

P{lacZ}cpo^l1

Cytology

Description

Insertion of P element at cytological position 90D, into an intron of cpo.

(Bellen et al., 1992)

Allele components

Component

Use(s)

Inserted element

P{lacZ}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal behavior (with cpo¹)

(Bellen et al., 1992)

abnormal behavior (with cpo²)

(Bellen et al., 1992)

abnormal flight (with cpo¹)

(Bellen et al., 1992)

abnormal flight (with cpo²)

(Bellen et al., 1992)

abnormal locomotor behavior | adult stage (with cpo¹)

(Bellen et al., 1992)

abnormal locomotor behavior | adult stage (with cpo²)

(Bellen et al., 1992)

abnormal phototaxis (with cpo¹)

(Bellen et al., 1992)

abnormal phototaxis (with cpo²)

(Bellen et al., 1992)

lethal - all die during embryonic stage | recessive

(Bellen et al., 1992)

some die during embryonic stage | recessive

(Bellen et al., 1992)

Phenotype Manifest In

Detailed Description

Statement

Reference

Behavioural defects in phototaxis, geotaxis, flight response and recovery from ether anaesthesia are seen when transheterozygous with either cpo¹ or cpo².

(Bellen et al., 1992)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

cpo^l1 has eye phenotype, non-enhanceable by Hsap\ATXN1^82Q.UAS/Scer\GAL4^GMR.PF

(Fernandez-Funez et al., 2000)

cpo^l1 has retina phenotype, non-enhanceable by Hsap\ATXN1^82Q.UAS/Scer\GAL4^GMR.PF

(Fernandez-Funez et al., 2000)

NOT suppressed by

Statement

Reference

cpo^l1 has eye phenotype, non-suppressible by Hsap\ATXN1^82Q.UAS/Scer\GAL4^GMR.PF

(Fernandez-Funez et al., 2000)

cpo^l1 has retina phenotype, non-suppressible by Hsap\ATXN1^82Q.UAS/Scer\GAL4^GMR.PF

(Fernandez-Funez et al., 2000)

NOT Enhancer of

Statement

Reference

cpo^l1 is a non-enhancer of eye phenotype of Hsap\ATXN1^82Q.UAS, Scer\GAL4^GMR.PF

(Fernandez-Funez et al., 2000)

cpo^l1 is a non-enhancer of retina phenotype of Hsap\ATXN1^82Q.UAS, Scer\GAL4^GMR.PF

(Fernandez-Funez et al., 2000)

NOT Suppressor of

Statement

Reference

cpo^l1 is a non-suppressor of eye phenotype of Hsap\ATXN1^82Q.UAS, Scer\GAL4^GMR.PF

(Fernandez-Funez et al., 2000)

cpo^l1 is a non-suppressor of retina phenotype of Hsap\ATXN1^82Q.UAS, Scer\GAL4^GMR.PF

(Fernandez-Funez et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

cpo^v3

(Bellen et al., 1992)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Allelic series of cpo alleles: cpo^lΔcp11 > cpo^l1 = cpo^l2 = cpo^l3 = cpo^l4 = cpo^l5 = cpo^l6 = cpo^j4A1 = cpo^l8 > cpo^l9 > cpo^lΔcp12 > cpo¹ = cpo².

(Bellen et al., 1992)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

5E8

cpo^L1

(Fernandez-Funez et al., 2000)

cpo^l1

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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