FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\haync2rv12
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General Information
Symbol
Dmel\haync2rv12
Species
D. melanogaster
Name
FlyBase ID
FBal0031459
Feature type
allele
Associated gene
Dmel\hay
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
diepoxybutane
(Mounkes and Fuller, 1999, Mounkes et al., 1992)
Progenitor genotype
haync2
(Mounkes and Fuller, 1999, Mounkes et al., 1992)
Cytology
Description

haync2rv12 has a deletion of the 5 amino acids 265-269, removing GAGKS in the P loop of the nucleotide-binding site.

(Mounkes and Fuller, 1999)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3L:10,632,542..10,632,557 [+]
Comment:

A deletion of 5 amino acids, removing GAGKS in the P loop of the nucleotide-binding site. The amino acid numbering differs between FBrf0108244 and the reference sequence. The positions and nature of the base substitutions in the mutants are derived from the sequence in Fig. 1 and from Table 1, and provide unambiguous assignments.

(Mounkes and Fuller, 1999)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      haync2rv12 is rescued by hay+t7.8

      (Mounkes et al., 1992)
      Comments

      Lethality rescued by genomic DNA fragment carrying hay transcription unit: rescued males are fertile.

      (Mounkes et al., 1992)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Mounkes and Schuske.

      (Mounkes et al., 1992)

      Selected as: a mutant that reverted the failure of haync2 to complement βTub85Dn.

      (Mounkes and Fuller, 1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      haync2rv12
      Name Synonyms
      Secondary FlyBase IDs
        References (2)