FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\hbhb1+hb2
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General Information
Symbol
Dmel\hbhb1+hb2
Species
D. melanogaster
Name
FlyBase ID
FBal0031468
Feature type
allele
Associated gene
Dmel\hb
Associated Insertion(s)
Carried in Construct
P{hbhb1+hb2}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Wharton and Struhl, 1991)
Progenitor genotype
hbΔ
(Wharton and Struhl, 1991)
Carried in construct
P{hbhb1+hb2}
Cytology
Description

Construct: Insertion of 145 bp sequence encoding hb1 and hb2 NREs 120 nucleotides downstream of hb coding region of hbΔ.

(Wharton and Struhl, 1991)
Allele components
Component
Use(s)
Encoded product / tool
hb
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos derived from females expressing hbhb1+hb2 show fully restored abdominal patterning compared to hbΔ. All eight abdominal segments are present.

      (Chen et al., 2008)

      hb protein is completely repressed in the posterior: larvae have normal abdominal segments.

      (Wharton and Struhl, 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      H(hb1+hb2)
      (Wharton and Struhl, 1991)
      hbhb1+hb2
      Name Synonyms
      Secondary FlyBase IDs
        References (2)