FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ifA7
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General Information
Symbol
Dmel\ifA7
Species
D. melanogaster
Name
FlyBase ID
FBal0031511
Feature type
allele
Associated gene
Dmel\if
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

loss of function allele

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Bloor and Brown, 1998)

loss of function allele

(Brabant and Brower, 1993)
Mutagen
ethyl methanesulfonate
(Bloor and Brown, 1998, Brabant and Brower, 1993)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos exhibit normal epidermis and resultant secreted cuticle, defects lie in internal tissues. Somatic muscle detach and round up. Gut morphogenesis is defective: anterior midgut does not become a slender tube and only two fat gastric caecae are formed. The ventral nerve cord does not fully condense.

      (Bloor and Brown, 1998)

      In 30 and 36 hour after pupariation (AP) ventral clones are associated with pronounced matrix-filled blisters.

      (Brabant et al., 1996)

      Clones in the eye do not exhibit photoreceptor disorganisation.

      (Brower et al., 1995)

      Extreme defects in somatic muscle attachment sites and morphogenesis of the midgut in the embryo. Muscles pull away from attachment sites at the onset of contractions. Ventral nerve cord fails to shorten completely. There is no dorsal herniation defect. Clonal analysis demonstrated that if function is only required in the cells of the ventral wing surface.

      (Brabant and Brower, 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT suppressed by
      Statement
      Reference

      ifA7 has wing | somatic clone phenotype, non-suppressible by Scer\GAL4684/mewUAS.cWa

      (Brabant et al., 1996)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Scer\GAL4684 induced expression of mewScer\UAS.cWa fails to rescue the blistering phenotype.

      (Brabant et al., 1996)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      ifA7 is rescued by Scer\GAL4684/ifC.UAS

      (Brabant et al., 1996)
      Comments

      Scer\GAL4684 induced expression of ifC.Scer\UAS rescues ifA7 ventral clones completely.

      (Brabant et al., 1996)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: F1 screen for mutations that fail to complement if3.

      (Bloor and Brown, 1998)
      Comments
      Comments

      Class 0 mutation.

      (Bloor and Brown, 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ifA7
      Name Synonyms
      Secondary FlyBase IDs
        References (4)