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General Information
Symbol
Dmel\rohs.PI
Species
D. melanogaster
Name
heat shock construct of Kimmel
FlyBase ID
FBal0032586
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

An Hsp70 promoter drives the expression of a ro fragment with a bacterial translation initiation sequence composed of both cDNA and genomic sequence which is missing the first intron, but contains the second intron and 3' untranslated region including the poly(A) site.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Ectopic rough expression inhibits movement of the morphogenetic furrow. dpp expression is abolished (as assayed with a dpp-lacZ fusion gene). Clonal analysis shows that this effect is non-autonomous, ectopic rough inhibits a diffusible signal required for morphogenetic furrow movement.

Viability is reduced in heat shocked embryos and larvae multiply heat shocked in the second half of larval life. Adults derived from heat shocked third instar larvae have severe defects; a single heat shock in mid to late-third instar results in a prominent scar near the middle of the eye, a single heat shock in late third instar or prepupa results in a reduced eye with the anterior third of the retina missing, and multiple heat shocks during the third instar results in eyes almost completely devoid of facets, and with very few photoreceptor cells. rohs.PI can partially rescue the eye phenotype of rox63 flies.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference

rohs.PI has visible phenotype, suppressible by amosRoi-1/amos[+]

Phenotype Manifest In
Suppressed by
Statement
Reference

rohs.PI has eye phenotype, suppressible by amosRoi-1/amos[+]

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
rohs.PI
rohs.PK
Name Synonyms
heat shock construct of Kimmel
Secondary FlyBase IDs
    References (3)