FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\robo17
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General Information
Symbol
Dmel\robo17
Species
D. melanogaster
Name
FlyBase ID
FBal0032594
Feature type
allele
Associated gene
Dmel\robo1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Kidd et al., 1998)
Mutagen
ethyl methanesulfonate
(Kidd et al., 1998, Seeger et al., 1993)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant embryos do not show transformation of the thoracic dch3 chordotonal organs to a morphology resembling that of abdominal lch5 chordotonal organs.

      (Kraut and Zinn, 2004)

      "Fuzzy commissure" phenotype in embryonic central nervous system.

      (Seeger et al., 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      robo17 is a non-suppressor of abnormal neuroanatomy phenotype of Scer\GAL4elav-C155, robo2EP2582

      (Kraut and Zinn, 2004)
      Phenotype Manifest In
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The transformation of abdominal lch5 chordotonal organs to a morphology resembling thoracic dch3 chordotonal organs that is seen in larvae expressing leaEP2582 under the control of Scer\GAL4elav-C155 is still seen if they are also mutant for robo7; 36.4% of abdominal segments have partial or complete transformation of the lch5 organs in the double mutant larvae. 11.2% of thoracic segments show transformation of the dch3 chordotonal organs to a morphology resembling that of abdominal lch5 chordotonal organs in robo7 leax135 double mutant embryos that are expressing leaScer\UAS.T:Hsap\MYC under the control of Scer\GAL4elav-C155. 16% of thoracic segments show transformation of the dch3 chordotonal organs to a morphology resembling that of abdominal lch5 chordotonal organs in robo7 leax135 double mutant embryos that are expressing leaScer\UAS.T:Hsap\MYC under the control of Scer\GAL448Y.

      (Kraut and Zinn, 2004)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Induced on: Fas3 null chromosome.

      (Kidd et al., 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Z2130
      (Kidd et al., 1998)
      robo17
      robo7
      roboZ2130
      (Kraut and Zinn, 2004)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)