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General Information
Symbol
Dmel\robo1
Species
D. melanogaster
Name
roundabout 1
Annotation Symbol
CG13521
Feature Type
FlyBase ID
FBgn0005631
Gene Model Status
Stock Availability
Gene Snapshot
roundabout 1 (robo1) encodes a member of the Robo receptor family that uses the secreted glycoprotein encoded by sli as ligand and the products of Sdc and Dscam1 as co-receptors. It contributes to axon guidance and dendrite morphogenesis as well as regulating trachea and heart tube development. [Date last reviewed: 2019-03-14]
Also Known As

robo, roundabout, Robo-1, dRobo, dRobo1

Key Links
Genomic Location
Cytogenetic map
Sequence location
2R:22,692,524..22,700,970 [-]
Recombination map

2-101

RefSeq locus
NT_033778 REGION:22692524..22700970
Sequence
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (29 terms)
Molecular Function (2 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
inferred from direct assay
inferred from physical interaction with FLYBASE:sli; FB:FBgn0264089
inferred from physical interaction with FLYBASE:Lrt; FB:FBgn0034540
inferred from physical interaction with UniProtKB:Q24139
inferred from physical interaction with UniProtKB:Q8T4F7
(assigned by UniProt )
Terms Based on Predictions or Assertions (0 terms)
Biological Process (18 terms)
Terms Based on Experimental Evidence (18 terms)
CV Term
Evidence
References
involved_in dendrite guidance
inferred from mutant phenotype
inferred from mutant phenotype
inferred from direct assay
involved_in gonad development
inferred from mutant phenotype
inferred from mutant phenotype
inferred from genetic interaction with FLYBASE:Dg; FB:FBgn0034072
inferred from genetic interaction with FLYBASE:Dys; FB:FBgn0260003
involved_in neuron recognition
inferred from mutant phenotype
inferred from genetic interaction with FLYBASE:robo2; FB:FBgn0002543
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from genetic interaction with FLYBASE:sli; FB:FBgn0264089
Terms Based on Predictions or Assertions (0 terms)
Cellular Component (9 terms)
Terms Based on Experimental Evidence (8 terms)
CV Term
Evidence
References
inferred from direct assay
located_in axon
located_in dendrite
inferred from direct assay
inferred from direct assay
located_in plasma membrane
inferred from direct assay
inferred from direct assay
(assigned by UniProt )
inferred from physical interaction with FLYBASE:Lrt; FB:FBgn0034540
inferred from direct assay
located_in vesicle
inferred from direct assay
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
inferred from sequence or structural similarity with EMBL:AF040990
Gene Group (FlyBase)
Protein Family (UniProt)
-
Summaries
Gene Group (FlyBase)
ROUNDABOUT -
The Roundabout genes encode transmembrane receptors that mediate repulsive cues by binding to midline repellent sli and regulate axon guidance. (Adapted from FBrf0210796).
Summary (Interactive Fly)

Ig and Fn repeats protein - a repulsive guidance receptor on growth cones that binds to Slit - Slit binding via the Ig1 domain is essential for midline repulsion by Drosophila Robo1 but dispensable for receptor expression, localization, and regulation

Gene Model and Products
Number of Transcripts
2
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\robo1 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.51

Sequence Ontology: Class of Gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
FBtr0071922
6392
1395
FBtr0343013
6698
1395
Additional Transcript Data and Comments
Reported size (kB)

7.5 (northern blot)

Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
FBpp0071833
151.8
1395
7.24
FBpp0309765
151.8
1395
7.24
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1395 aa isoforms: robo1-PA, robo1-PC
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\robo1 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
No Assay Recorded
Stage
Tissue/Position (including subcellular localization)
Reference
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
olfactory receptor neuron
axon

Comment: 0-24 hr APF; surface of antennal lobe

antennal lobe glomerulus | subset
axon

Comment: at 60 hr APF; several glomeruli, not identified

western blot
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data

At stage 13 robo protein is expressed at higher levels on growth cones and filopodia in the longitudinal tracts than on the axons themselves. Very low levels are observed on the surface of commissural axons and robo-positive vessels can be seen inside the commissural axons.

robo protein has widespread and diffuse expression in the adult brain. It is expressed in all neuropil regions. The projection of clock neurons labelled by Pdf or Scer\GAL4tim.PE colocalise with domains of robo expression, whereas the cell bodies do not.

In filleted stage 17 embryos, robo1 is detected in the dendritic arborizing neurons and in the dendrites. In larval stages, expression is observed in the class I and class IV dendritic arborizing neurons and in the initial dendritic segments.

also expressed at muscle insertion sites of embryonic CNS in stage 16 embryos

robo protein is weakly expressed in the cell bodies of embryonic chordotonal neurons. It is strongly expressed in the tips of the dendrites of chordotonal neurons.

robo and robo2 are detected in epidermal cells including the ventral sensory precursor cells. robo3 is not detected at any time in epidermal cells.

robo1, robo2, and robo3 proteins are expressed in overlapping patterns in the larval central nervous system and developing visual system.

robo protein is detected weakly in the cell bodies of the dorsal cluster sensory neurons in mid stage 13 embryos just prior to axon outgrowth. Stronger robo staining is detected on outgrowing projections from these neurons through stage 15. robo protein is also detected on the projections of lch5 chordotonal neurons in stage 14. From late stage 13, robo is expressed in longitudinal muscle epidermal attachment sites.

robo protein is first observed in weak lateral stripes during germ band elongation. At the beginning of germ band retraction, it is observed in the neurectoderm. Beginning at the end of stage 12, robo protein is expressed in the growth cones which project ipsilaterally. These include aCC, pCC, MP1, dMP2 and vMP2. No expression is seen on commissural growth cones as they extend across the midline but when they turn to project longitudinally, expression dramatically increases. robo protein is expressed at high levels on all longitudinally projecting growth cones. robo protein is also expressed weakly throughout the epidermis and at a higher level at muscle attachment sites. Faint staining is observed in the commissures in stages 16 and 17.

Marker for
 
Subcellular Localization
CV Term
Evidence
References
inferred from direct assay
located_in axon
located_in dendrite
inferred from direct assay
inferred from direct assay
located_in plasma membrane
inferred from direct assay
inferred from direct assay
(assigned by UniProt )
inferred from physical interaction with FLYBASE:Lrt; FB:FBgn0034540
inferred from direct assay
located_in vesicle
inferred from direct assay
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\robo1 in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 31 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 49 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of robo1
Transgenic constructs containing regulatory region of robo1
Aberrations (Deficiencies and Duplications) ( 8 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
Sterility
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
abdominal basiconical sensillum dbd & embryo & nerve terminal
antennal glomerulus DM2 & olfactory neuron, with Scer\GAL4lz-gal4
antennal glomerulus DM6 & olfactory neuron, with Scer\GAL4lz-gal4
axon & pCC neuron
chordotonal organ & axon | lateral
chordotonal organ & embryo & nerve terminal
tergal depressor of trochanter muscle motor neuron & dendrite, with Scer\GAL4shakB.lethal.4.1
Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (14)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
11 of 15
Yes
Yes
9 of 15
No
Yes
1  
8 of 15
No
Yes
3 of 15
No
No
1 of 15
No
Yes
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
Yes
1 of 15
No
No
1 of 15
No
No
1 of 15
No
Yes
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (13)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
12 of 15
Yes
Yes
9 of 15
No
Yes
8 of 15
No
Yes
4 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
Yes
1 of 15
No
No
1 of 15
No
No
1 of 15
No
Yes
Rattus norvegicus (Norway rat) (13)
7 of 13
Yes
Yes
6 of 13
No
Yes
6 of 13
No
Yes
2 of 13
No
No
2 of 13
No
No
1 of 13
No
Yes
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
Yes
1 of 13
No
Yes
Xenopus tropicalis (Western clawed frog) (9)
5 of 12
Yes
Yes
4 of 12
No
Yes
2 of 12
No
Yes
2 of 12
No
No
1 of 12
No
Yes
1 of 12
No
No
1 of 12
No
No
1 of 12
No
No
1 of 12
No
Yes
Danio rerio (Zebrafish) (17)
9 of 15
Yes
Yes
7 of 15
No
Yes
4 of 15
No
Yes
4 of 15
No
No
2 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
No
1 of 15
No
Yes
1 of 15
No
No
1 of 15
No
No
1 of 15
No
Yes
1 of 15
No
No
1 of 15
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (1)
10 of 15
Yes
Yes
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (0)
No records found.
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091900PT )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Drosophila simulans
Drosophila sechellia
Drosophila erecta
Drosophila yakuba
Drosophila ananassae
Drosophila pseudoobscura pseudoobscura
Drosophila persimilis
Drosophila willistoni
Drosophila virilis
Drosophila mojavensis
Drosophila grimshawi
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091500SC )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Musca domestica
House fly
Glossina morsitans
Tsetse fly
Lucilia cuprina
Australian sheep blowfly
Mayetiola destructor
Hessian fly
Aedes aegypti
Yellow fever mosquito
Aedes aegypti
Yellow fever mosquito
Anopheles darlingi
American malaria mosquito
Anopheles darlingi
American malaria mosquito
Anopheles gambiae
Malaria mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W00V4 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Apis florea
Little honeybee
Apis mellifera
Western honey bee
Bombus impatiens
Common eastern bumble bee
Bombus terrestris
Buff-tailed bumblebee
Linepithema humile
Argentine ant
Megachile rotundata
Alfalfa leafcutting bee
Nasonia vitripennis
Parasitic wasp
Dendroctonus ponderosae
Mountain pine beetle
Dendroctonus ponderosae
Mountain pine beetle
Tribolium castaneum
Red flour beetle
Pediculus humanus
Human body louse
Rhodnius prolixus
Kissing bug
Rhodnius prolixus
Kissing bug
Rhodnius prolixus
Kissing bug
Rhodnius prolixus
Kissing bug
Rhodnius prolixus
Kissing bug
Cimex lectularius
Bed bug
Cimex lectularius
Bed bug
Cimex lectularius
Bed bug
Acyrthosiphon pisum
Pea aphid
Zootermopsis nevadensis
Nevada dampwood termite
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X01XJ )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Ixodes scapularis
Black-legged tick
Ixodes scapularis
Black-legged tick
Ixodes scapularis
Black-legged tick
Ixodes scapularis
Black-legged tick
Stegodyphus mimosarum
African social velvet spider
Stegodyphus mimosarum
African social velvet spider
Stegodyphus mimosarum
African social velvet spider
Stegodyphus mimosarum
African social velvet spider
Tetranychus urticae
Two-spotted spider mite
Daphnia pulex
Water flea
Daphnia pulex
Water flea
Daphnia pulex
Water flea
Daphnia pulex
Water flea
Daphnia pulex
Water flea
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G02YA )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (17)
3 of 10
3 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 1 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    esyN Network Diagram
    Show neighbor-neighbor interactions:
    Select Layout:
    Legend:
    Protein
    RNA
    Selected Interactor(s)
    Interactions Browser

    Please see the Physical Interaction reports below for full details
    protein-protein
    Physical Interaction
    Assay
    References
    Summary of Genetic Interactions
    esyN Network Diagram
    esyN Network Key:
    Suppression
    Enhancement

    Please look at the allele data for full details of the genetic interactions
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    External Data
    Linkouts
    BioGRID - A database of protein and genetic interactions.
    DroID - A comprehensive database of gene and protein interactions.
    InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
    MIST (genetic) - An integrated Molecular Interaction Database
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Pathways
    Signaling Pathways (FlyBase)
    Metabolic Pathways
    External Data
    Genomic Location and Detailed Mapping Data
    Chromosome (arm)
    2R
    Recombination map

    2-101

    Cytogenetic map
    Sequence location
    2R:22,692,524..22,700,970 [-]
    FlyBase Computed Cytological Location
    Cytogenetic map
    Evidence for location
    59A2-59A3
    Limits computationally determined from genome sequence between P{EP}ppaEP698&P{EP}EP2184 and P{PZ}blw03972
    Experimentally Determined Cytological Location
    Cytogenetic map
    Notes
    References
    Experimentally Determined Recombination Data
    Right of (cM)
    Notes

    Maps close to px.

    Stocks and Reagents
    Stocks (20)
    Genomic Clones (21)
    cDNA Clones (65)
     

    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

    cDNA clones, fully sequenced
    BDGP DGC clones
      Other clones
      Drosophila Genomics Resource Center cDNA clones

      For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

      cDNA Clones, End Sequenced (ESTs)
      BDGP DGC clones
      RNAi and Array Information
      Linkouts
      DRSC - Results frm RNAi screens
      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
      Antibody Information
      Laboratory Generated Antibodies
       

      monoclonal, polyclonal

      Commercially Available Antibodies
       
      Developmental Studies Hybridoma Bank - Monoclonal antibodies for use in research
      Other Information
      Relationship to Other Genes
      Source for database identify of

      Source for identity of: robo1 robo

      Source for database merge of

      Source for merge of: robo BEST:GM07780

      Additional comments
      Other Comments

      The lateral positioning of longitudinal axon pathways in the embryo relies primarily on differences in robo gene regulation, not on distinct combinations of the three robo proteins (robo, lea and robo3) as previously thought. However, the unique structural features of robo are required to prevent midline crossing and the unique structural features of lea are required to promote midline crossing.

      Nonsense-mediated mRNA decay (NMD) down-regulates a distinct splice isoform(s) of this gene.

      The period of locomotor activity is shortened in robo mutants.

      dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.

      robo and comm form a stable complex in S2 cells.

      robo is transiently required to stop longitudinal glia migration short of the midline, though is not responsible for restricting glial movement from the time that the glia contact the axons.

      low levels of lea or robo and robo3 have both distinct and overlapping functions in controlling pathway choices within the central nervous system.

      lea and robo work together to control repulsive axon guidance in the midline of the embryonic ventral cord.

      The cytoplasmic domain of the guidance receptor robo can determine the growth cones' response in vivo, mediating repulsion independently of the ectodomain and its particular ligand binding.

      Four EMS induced alleles were identified in a screen for mutations affecting commissure formation in the CNS of the embryo.

      Mutant analysis suggests that robo function is dosage sensitive.

      The robo gene product both repels growth cones at the midline and inhibits branching throughout the neuropile by promoting filopodial retraction.

      robo has been cloned and sequenced.

      robo appears to function as a gatekeeper controlling midline crossing.

      comm downregulates robo expression.

      Mutations in 12 complementation groups differentially affect lateral chordotonal axon growth, fasciculation or ventral orientation. Mutations in robo, spen, sli and los cause lch axon defasciculation.

      The robo gene product plays a role in the repulsive signalling system, a component of the mechanism that guides growth cones towards and away from the midline. In mutant embryos the growth cones that normally extend only on their own side of the central nervous system (CNS) now project across the midline of one of the commissures.

      Mutant alleles have "fuzzy commisure" phenotype in embryonic central nervous system.

      Origin and Etymology
      Discoverer
      Etymology
      Identification
      External Crossreferences and Linkouts ( 50 )
      Sequence Crossreferences
      NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
      RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
      UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
      Other crossreferences
      Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
      Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
      Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
      Flygut - An atlas of the Drosophila adult midgut
      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
      KEGG Genes - Molecular building blocks of life in the genomic space.
      modMine - A data warehouse for the modENCODE project
      Linkouts
      BioGRID - A database of protein and genetic interactions.
      DroID - A comprehensive database of gene and protein interactions.
      DRSC - Results frm RNAi screens
      Developmental Studies Hybridoma Bank - Monoclonal antibodies for use in research
      FLIGHT - Cell culture data for RNAi and other high-throughput technologies
      FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
      FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
      FlyMine - An integrated database for Drosophila genomics
      Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
      InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
      MIST (genetic) - An integrated Molecular Interaction Database
      MIST (protein-protein) - An integrated Molecular Interaction Database
      Synonyms and Secondary IDs (18)
      Reported As
      Symbol Synonym
      BEST:GM07780
      D-Robo1
      robo
      (Manhart et al., 2020, Xu et al., 2020, Gonsior and Ismat, 2019, Simonetti et al., 2019, Mitchell, 2018, Aw et al., 2017, Hernandez-Fleming et al., 2017, Oliva et al., 2016, Raza and Jacobs, 2016, Sarov et al., 2016, Berni, 2015, Chance and Bashaw, 2015, Bosch, 2014.11.5, Cantera et al., 2014, Jalvingh et al., 2014, Weitkunat and Schnorrer, 2014, Wolfram et al., 2014, Zarin et al., 2014, Zhang et al., 2014, Harpaz et al., 2013, O'Donnell and Bashaw, 2013, Ozkan et al., 2013, Ozkan et al., 2013, Evans and Bashaw, 2012, Vanderploeg et al., 2012, Knox et al., 2011, Kucherenko et al., 2011, Lee et al., 2011, Marrone et al., 2011, Shulman et al., 2011, Smart et al., 2011, Song et al., 2011, Weyers et al., 2011, Carrillo et al., 2010, Coleman et al., 2010, Deng et al., 2010, Dorsten et al., 2010, Evans and Bashaw, 2010, Evans and Bashaw, 2010, Evans et al., 2010, Mellert et al., 2010, Wright et al., 2010, Al-Anzi and Wyman, 2009, Bahri et al., 2009, Hansen et al., 2009, Liu et al., 2009, Liu et al., 2009, Mauss et al., 2009, Wayburn and Volk, 2009, Yamamoto et al., 2009, Yang et al., 2009, Zlatic et al., 2009, Andrews and Kidd, 2008, Berni et al., 2008, Dimitrova et al., 2008, Gilestro, 2008, Kucherenko et al., 2008, Medioni et al., 2008, Ou et al., 2008, Santiago-Martínez et al., 2008, Yamamoto et al., 2008, Zmojdzian et al., 2008, Bhat et al., 2007, Chen et al., 2007, Dietzl et al., 2007, Furrer et al., 2007, Garbe and Bashaw, 2007, Garbe et al., 2007, Garbe et al., 2007, Grueber et al., 2007, Lee et al., 2007, Magalhaes et al., 2007, Simionato et al., 2007, Yamamoto et al., 2007, Zhang et al., 2007, Cardoso et al., 2006, Chilton, 2006, Hiramoto and Hiromi, 2006, Sandmann et al., 2006, Santiago-Martinez et al., 2006, Sun et al., 2006, Yang and Bashaw, 2006, Hannula-Jouppi et al., 2005, Keleman et al., 2005, Merianda et al., 2005, Sano et al., 2005, Matsuura et al., 2004, Fan et al., 2003, Furrer et al., 2003, Hsouna et al., 2003, Englund et al., 2002, Myat et al., 2002, Kim et al., 2001, Kidd et al., 1999)
      Secondary FlyBase IDs
      • FBgn0045796
      Datasets (0)
      Study focus (0)
      Experimental Role
      Project
      Project Type
      Title
      References (434)