FlyBase Gene Report: Dmel\dpr13

General Information

Symbol

Dmel\dpr13

Species

D. melanogaster

Name

defective proboscis extension response 13

Annotation Symbol

CG33996

Feature Type

protein_coding_gene

FlyBase ID

FBgn0034286

Gene Model Status

Current

Stock Availability

22 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

Dm_2R:58906

Key Links

Genomic Location

Cytogenetic map

55A3-55A3

Sequence location

2R:17,975,122..18,007,902 [-]

Recombination map

2-84

RefSeq locus

NT_033778 REGION:17975122..18007902

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (4 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in synapse organization

inferred from expression pattern

(Carrillo et al., 2015)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

involved_in sensory perception of chemical stimulus

inferred from sequence or structural similarity with FLYBASE:dpr1; FB:FBgn0040726

(Nakamura et al., 2002)

involved_in synapse organization

inferred from biological aspect of ancestor with PANTHER:PTN000589413

(GO Reference Genome Project, 2011-)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

is_active_in neuron projection membrane

inferred from biological aspect of ancestor with PANTHER:PTN000589413

(GO Reference Genome Project, 2011-)

located_in plasma membrane

inferred from sequence model

(Ozkan et al., 2013)

Gene Group (FlyBase)

DEFECTIVE PROBOSCIS EXTENSION RESPONSE

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

DEFECTIVE PROBOSCIS EXTENSION RESPONSE -: Defective proboscis extension response (Dpr) cell surface proteins are members of the immunoglobulin superfamily. They form a complex interaction network with Dpr-interacting proteins (DIPs), acting as neuronal surface labels in the specificity of synaptic connections between neurons and target cells. (Adapted from FBrf0230454 and FBrf0149073).

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\dpr13 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry A1ZB15)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.50

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

dpr13-RB

FBtr0300215

NM_001038867

3283

419

dpr13-RC

FBtr0340286

NM_001299626

3119

418

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

dpr13-PB

FBpp0289452

45.8

419

7.12

FBpp0309247

45.7

418

7.24

A0A0B4LFL9

NP_001286555

AHN56351

Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\dpr13 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.61

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 13 -- 16

dorsal sensory complex proper primordium

Comment: reported as dorsal/lateral sensory complexes

(Fisher et al., 2012)

embryonic brain

(Fisher et al., 2012)

larval ventral nerve cord

(Fisher et al., 2012)

ventral sensory complex primordium

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

Reporter: Mi{Trojan-GAL4.0}dpr13^{MI05577-TG4.0}

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

leg muscle motor neuron | subset

(Venkatasubramanian et al., 2019)

adult sensory neuron | subset of leg

(Venkatasubramanian et al., 2019)

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\dpr13 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\dpr13

View exonic expression by tissue for Dmel\dpr13

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0034286

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

3885598/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0034286

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0034286

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0034286

Flygut - An atlas of the Drosophila adult midgut

FBgn0034286

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 6 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 5 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of dpr13

Transgenic constructs containing regulatory region of dpr13

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 5 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

dpr13^GD8347

viable, with Scer\GAL4^Mef2.PR

dpr13^GD8347

viable, with Scer\GAL4^pnr-MD237

dpr13^GD8347

Other Phenotypes

Allele

abnormal sleep | adult stage | female

dpr13^MB08759

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (86)

Hsap\CD86

3 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

Yes

Hsap\BTN2A1

1 of 14

Yes

Hsap\BTN2A2

1 of 14

Yes

Hsap\BTN2A3P

1 of 14

Yes

Hsap\BTN3A1

1 of 14

Yes

Hsap\BTN3A2

1 of 14

Yes

Hsap\BTN3A3

1 of 14

Yes

Hsap\BTNL3

1 of 14

Yes

Hsap\BTNL8

1 of 14

Yes

Hsap\BTNL10

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\CD276

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\FCRL5

1 of 14

Yes

Hsap\FGFRL1

1 of 14

Hsap\FLT4

1 of 14

Hsap\HHLA2

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\MYOM2

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\UNC5D

1 of 14

Hsap\USH2A

1 of 14

Hsap\VSIG2

1 of 14

Yes

Hsap\VTCN1

1 of 14

Yes

Hsap\WFIKKN2

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (63)

Rnor\Cadm2

2 of 14

Yes

Rnor\Cadm3

2 of 14

Yes

Rnor\Cadm4

2 of 14

Yes

Rnor\Cd86

2 of 14

Yes

Rnor\Dscaml1

2 of 14

Yes

Rnor\Hmcn1

2 of 14

Yes

Rnor\Iglon5

2 of 14

Yes

Rnor\Kirrel1

2 of 14

Yes

Rnor\Kirrel3

2 of 14

Yes

Rnor\Lsamp

2 of 14

Yes

Rnor\Ncam1

2 of 14

Yes

Rnor\Opcml

2 of 14

Yes

Rnor\Sdk2

2 of 14

Yes

Rnor\Bsg

1 of 14

Rnor\Btn1a1

1 of 14

Rnor\Btn2a2

1 of 14

Yes

Rnor\Btnl2

1 of 14

Yes

Rnor\Btnl3

1 of 14

Yes

Rnor\Btnl5

1 of 14

Yes

Rnor\Btnl7

1 of 14

Rnor\Btnl8

1 of 14

Yes

Rnor\Btnl9

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\Cd276

1 of 14

Yes

Rnor\Cntn2

1 of 14

Rnor\Crtam

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\Fgfrl1

1 of 14

Rnor\Flt4

1 of 14

Rnor\Gpa33

1 of 14

Yes

Rnor\Icoslg

1 of 14

Rnor\Igdcc4

1 of 14

Rnor\Igsf5

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\Slamf9

1 of 14

Yes

Rnor\Tyro3

1 of 14

Yes

Rnor\Unc5d

1 of 14

Rnor\Vtcn1

1 of 14

Yes

Mus musculus (laboratory mouse) (67)

Mmus\Cadm2

2 of 14

Yes

Mmus\Cadm3

2 of 14

Yes

Mmus\Cadm4

2 of 14

Yes

Mmus\Dscaml1

2 of 14

Yes

Mmus\Iglon5

2 of 14

Yes

Mmus\Kirrel3

2 of 14

Yes

Mmus\Kirrel

2 of 14

Yes

Mmus\Ncam1

2 of 14

Yes

Mmus\Negr1

2 of 14

Yes

Mmus\Ntm

2 of 14

Yes

Mmus\Opcml

2 of 14

Yes

Mmus\Sdk1

2 of 14

Yes

Mmus\Sdk2

2 of 14

Yes

Mmus\Btn1a1

1 of 14

Mmus\Btn2a2

1 of 14

Yes

Mmus\Btnl1

1 of 14

Yes

Mmus\Btnl2

1 of 14

Yes

Mmus\Btnl4

1 of 14

Yes

Mmus\Btnl6

1 of 14

Yes

Mmus\Btnl9

1 of 14

Yes

Mmus\Btnl10

1 of 14

Mmus\Cadm1

1 of 14

Mmus\Cd80

1 of 14

Yes

Mmus\Cd86

1 of 14

Yes

Mmus\Cd274

1 of 14

Yes

Mmus\Cd276

1 of 14

Yes

Mmus\Cntn2

1 of 14

Mmus\Cntn3

1 of 14

Mmus\Crtam

1 of 14

Yes

Mmus\Dcc

1 of 14

Mmus\Dscam

1 of 14

Mmus\Ermap

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Mmus\Igsf9b

1 of 14

Mmus\Igsf9

1 of 14

Mmus\Igsf11

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Mmus\Skint7

1 of 14

Yes

Mmus\Ttn

1 of 14

Mmus\Tyro3

1 of 14

Yes

Mmus\Unc5d

1 of 14

Mmus\Vtcn1

1 of 14

Yes

Xenopus tropicalis (Western clawed frog) (34)

Xtro\cadm2

2 of 13

Yes

Xtro\iglon5

2 of 13

Yes

Xtro\arsb

1 of 13

Xtro\cadm1

1 of 13

Xtro\cadm3

1 of 13

Yes

Xtro\cadm4

1 of 13

Yes

Xtro\cd86

1 of 13

Yes

Xtro\cd276

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\rplp0

1 of 13

Xtro\slc35g1

1 of 13

Xtro\spata1

1 of 13

Yes

Xtro\ttn

1 of 13

Xtro\tyro3

1 of 13

Yes

Xtro\XB5805949

1 of 13

Yes

Danio rerio (Zebrafish) (91)

Drer\cntn3a.1

2 of 14

Yes

Drer\cntn4

2 of 14

Yes

Drer\dscama

2 of 14

Yes

Drer\dscamb

2 of 14

Yes

Drer\havcr2

2 of 14

Yes

Drer\igsf9ba

2 of 14

Yes

Drer\kirrel1b

2 of 14

Yes

Drer\nectin3a

2 of 14

Yes

Drer\negr1

2 of 14

Yes

Drer\opcml

2 of 14

Yes

Drer\pvrl2l

2 of 14

Yes

Drer\sdk1a

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\cd276

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\dicp1.19

1 of 14

Yes

Drer\dscaml1

1 of 14

Drer\fgfrl1b

1 of 14

Drer\havcr1

1 of 14

Yes

Drer\hhla2a.2

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\LOC110439013

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\myot

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Drer\si:ch211-159i8.4

1 of 14

Drer\si:ch211-264f5.6

1 of 14

Drer\si:dkey-22i16.9

1 of 14

Yes

Drer\si:dkey-24p1.7

1 of 14

Drer\si:dkey-71p21.13

1 of 14

Drer\si:dkey-208m12.2

1 of 14

Yes

Drer\timd4

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\zgc:123297

1 of 14

Yes

Drer\zgc:152904

1 of 14

Drer\zgc:153911

1 of 14

Drer\zgc:162154

1 of 14

Yes

Drer\zgc:165604

1 of 14

Yes

Drer\zgc:172120

1 of 14

Drer\zgc:194627

1 of 14

Yes

Caenorhabditis elegans (Nematode, roundworm) (20)

Cele\zig-8

7 of 14

Yes

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Anopheles gambiae (African malaria mosquito) (77)

Agam\AgaP_AGAP009183

10 of 12

Yes

Agam\AgaP_AGAP012441

7 of 12

Yes

5 of 12

5 of 12

4 of 12

4 of 12

4 of 12

4 of 12

4 of 12

4 of 12

Yes

4 of 12

4 of 12

4 of 12

4 of 12

4 of 12

4 of 12

4 of 12

4 of 12

4 of 12

3 of 12

3 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (0)

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:dpr13. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (67)

8 of 13

8 of 13

7 of 13

7 of 13

7 of 13

7 of 13

7 of 13

7 of 13

7 of 13

6 of 13

6 of 13

6 of 13

6 of 13

6 of 13

6 of 13

5 of 13

5 of 13

5 of 13

5 of 13

5 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

Ama

2 of 13

bdl

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

klg

2 of 13

Lac

2 of 13

rst

2 of 13

sdk

2 of 13

tutl

2 of 13

babos

1 of 13

boi

1 of 13

btl

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

fra

1 of 13

ImpL2

1 of 13

Nrg

1 of 13

Ppn

1 of 13

Pxn

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

sls

1 of 13

sns

1 of 13

Strn-Mlck

1 of 13

trol

1 of 13

wrapper

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

CD86; CD86 molecule

3 of 14

601020

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

dpr13 - DIP-ε

enzyme linked immunosorbent assay, surface plasmon resonance, predetermined participant

(Cosmanescu et al., 2018, Carrillo et al., 2015, Ozkan et al., 2013)

dpr13 - DIP-ζ

enzyme linked immunosorbent assay, surface plasmon resonance, predetermined participant

(Cosmanescu et al., 2018, Carrillo et al., 2015, Ozkan et al., 2013)

dpr13 - cDIP

enzyme linked immunosorbent assay

(Carrillo et al., 2015, Ozkan et al., 2013)

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0034286

MIST (protein-protein) - An integrated Molecular Interaction Database

3885598

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-84

Cytogenetic map

55A3-55A3

Sequence location

2R:17,975,122..18,007,902 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

55A3-55A3

Limits computationally determined from genome sequence between P{PZ}grh⁰⁶⁸⁵⁰&P{lacW}olf186-F^k11505 and P{PZ}Hsf⁰³⁰⁹¹&P{EP}Dgp-1^EP731

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-84

(FlyBase, 2016)

2-88.0

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (22)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

40712

w¹¹¹⁸; P{GMR95F09-GAL4}attP2

71150

w¹¹¹⁸; P{R95F09-p65.AD}attP40

600867

w¹¹¹⁸; P{R95F12-p65.AD}attP40

75701

w¹¹¹⁸; P{R95F12-GAL4.DBD}attP2

601707

w¹¹¹⁸; PBac{R95F09-p65.AD}VK00027

601756

w¹¹¹⁸ P{R95F09-p65.AD}su(Hw)attP8

26401

w¹¹¹⁸; Mi{ET1}dpr13^MB08759

76013

w¹¹¹⁸; P{R30A10-p65.AD}attP40; P{R95F09-GAL4.DBD}attP2

86708

w¹¹¹⁸; P{R64B08-p65.AD}attP40; P{R95F09-GAL4.DBD}attP2

87017

w¹¹¹⁸; P{R95F12-p65.AD}attP40; P{R15A04-GAL4.DBD}attP2

VDRC

v107676

P{KK112959}VIE-260B

v17668

w¹¹¹⁸; P{GD8347}v17668/TM3

More stocks available...

Genomic Clones (27)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (21)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

IP04017

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0034286

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0034286

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Relationship to Other Genes

Source for database merge of

Source for merge of: dpr13 CG14493

(FlyBase Genome Annotators, 2005)

Additional comments

Annotations CG12557 and CG14493 merged as CG33996 (which corresponds to dpr13) in release 4.3 of the genome annotation.

(FlyBase Genome Annotators, 2005)

Nomenclature History

Source for database identify of

Source for identity of: dpr13 CG12557

(Nakamura et al., 2002)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (9)

Reported As

Symbol Synonym

CG12557

(Vogel et al., 2003)

CG14493

CG33996

(National Institute of Genetics Fly Stocks, 2022-, Keleman et al., 2009.8.5, Lebo et al., 2009, FlyBase Genome Annotators, 2005)

CT34204

(Hynes and Zhao, 2000)

Dm_2R:58906

(FlyBase Genome Annotators, 2014, Ladoukakis et al., 2011)

Dpr-13

(Vogel et al., 2003)

Dpr13

(Lobb-Rabe et al., 2024, Nandigrami et al., 2022, Cosmanescu et al., 2018, Zinn and Özkan, 2017, Carrillo et al., 2015, Ozkan et al., 2013)

dpr13

(Corthals et al., 2023, Velten et al., 2022, Wang et al., 2022, Kurmangaliyev et al., 2020, Lobell et al., 2017, Gene Disruption Project members, 2015-, Ashwal-Fluss et al., 2014, Vernes, 2014, Ozkan et al., 2013, Ozkan et al., 2013, Pool et al., 2012, Lebo et al., 2009, Nakamura et al., 2002)

Name Synonyms

defective proboscis extension response 13

dpr13

Secondary FlyBase IDs

FBgn0034287
FBgn0053996
FBtr0086815
FBpp0085994
FBtr0086816
FBpp0085995

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 40 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

3885598

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

A1ZB15

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

A1ZB15

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0034286

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

3885598/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0034286

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0034286

FlyMine - An integrated database for Drosophila genomics

FBgn0034286

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG33996

MARRVEL_MODEL - MARRVEL (model organism gene)

3885598

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0034286

DroID - A comprehensive database of gene and protein interactions.

FBgn0034286

DRSC - Results frm RNAi screens

FBgn0034286

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0034286

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0034286

Flygut - An atlas of the Drosophila adult midgut

FBgn0034286

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

MIST (protein-protein) - An integrated Molecular Interaction Database

3885598

References (49)

The following external sites may use different assemblies or annotations than FlyBase.

-0.61

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