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General Information
Symbol
Dmel\dpr21
Species
D. melanogaster
Name
defective proboscis extension response 21
Annotation Symbol
CG42596
Feature Type
FlyBase ID
FBgn0260995
Gene Model Status
Stock Availability
Gene Summary
Contribute a Gene Snapshot for this gene.
Key Links
Genomic Location
Cytogenetic map
Sequence location
Recombination map
2-55
RefSeq locus
NT_033778 REGION:3066499..3191011
Sequence
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (2 terms)
Molecular Function (0 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Biological Process (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
inferred from expression pattern
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
inferred from biological aspect of ancestor with PANTHER:PTN000589413
(assigned by GO_Central )
Cellular Component (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
inferred from biological aspect of ancestor with PANTHER:PTN000589413
(assigned by GO_Central )
Protein Family (UniProt)
-
Summaries
Gene Group (FlyBase)
DEFECTIVE PROBOSCIS EXTENSION RESPONSE -
Defective proboscis extension response (Dpr) cell surface proteins are members of the immunoglobulin superfamily. They form a complex interaction network with Dpr-interacting proteins (DIPs), acting as neuronal surface labels in the specificity of synaptic connections between neurons and target cells. (Adapted from FBrf0230454 and FBrf0149073).
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\dpr21 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.47

Sequence Ontology: Class of Gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
FBtr0334939
993
282
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
FBpp0306958
31.5
282
7.77
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\dpr21 using the Feature Mapper tool.

External Data
Crossreferences
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\dpr21 in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Images
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 2 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of dpr21
Transgenic constructs containing regulatory region of dpr21
Aberrations (Deficiencies and Duplications) ( 0 )
Inferred from experimentation ( 0 )
Inferred from location ( 0 )
    Alleles Representing Disease-Implicated Variants
    Phenotypes
    For more details about a specific phenotype click on the relevant allele symbol.
    Phenotype manifest in
    Allele
    Orthologs
    Human Orthologs (via DIOPT v8.0)
    Homo sapiens (Human) (25)
    Species\Gene Symbol
    Score
    Best Score
    Best Reverse Score
    Alignment
    Complementation?
    Transgene?
    1 of 15
    Yes
    No
    1 of 15
    Yes
    Yes
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    3  
    1 of 15
    Yes
    No
    2  
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    2  
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    Yes
    1 of 15
    Yes
    Yes
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    4  
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1  
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1  
    1 of 15
    Yes
    Yes
    Model Organism Orthologs (via DIOPT v8.0)
    Mus musculus (laboratory mouse) (22)
    Species\Gene Symbol
    Score
    Best Score
    Best Reverse Score
    Alignment
    Complementation?
    Transgene?
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1  
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    Yes
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1  
    1 of 15
    Yes
    No
    1  
    1 of 15
    Yes
    No
    1  
    1 of 15
    Yes
    Yes
    1 of 15
    Yes
    Yes
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    Rattus norvegicus (Norway rat) (17)
    1 of 13
    Yes
    No
    1 of 13
    Yes
    No
    1 of 13
    Yes
    No
    1 of 13
    Yes
    No
    1 of 13
    Yes
    No
    1 of 13
    Yes
    No
    1 of 13
    Yes
    No
    1 of 13
    Yes
    No
    1 of 13
    Yes
    No
    1 of 13
    Yes
    No
    1 of 13
    Yes
    No
    1 of 13
    Yes
    No
    1 of 13
    Yes
    No
    1 of 13
    Yes
    No
    1 of 13
    Yes
    No
    1 of 13
    Yes
    No
    1 of 13
    Yes
    No
    Xenopus tropicalis (Western clawed frog) (13)
    1 of 12
    Yes
    No
    1 of 12
    Yes
    No
    1 of 12
    Yes
    No
    1 of 12
    Yes
    No
    1 of 12
    Yes
    No
    1 of 12
    Yes
    No
    1 of 12
    Yes
    Yes
    1 of 12
    Yes
    Yes
    1 of 12
    Yes
    No
    1 of 12
    Yes
    No
    1 of 12
    Yes
    No
    1 of 12
    Yes
    No
    1 of 12
    Yes
    No
    Danio rerio (Zebrafish) (35)
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    Yes
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    Yes
    1 of 15
    Yes
    Yes
    1 of 15
    Yes
    Yes
    1 of 15
    Yes
    Yes
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    No
    1 of 15
    Yes
    Yes
    1 of 15
    Yes
    Yes
    1 of 15
    Yes
    No
    Caenorhabditis elegans (Nematode, roundworm) (14)
    7 of 15
    Yes
    No
    1 of 15
    No
    Yes
    1 of 15
    No
    No
    1 of 15
    No
    No
    1 of 15
    No
    Yes
    1 of 15
    No
    No
    1 of 15
    No
    No
    1 of 15
    No
    No
    1 of 15
    No
    No
    1 of 15
    No
    No
    1 of 15
    No
    No
    1 of 15
    No
    No
    1 of 15
    No
    No
    1 of 15
    No
    Yes
    Arabidopsis thaliana (thale-cress) (0)
    No records found.
    Saccharomyces cerevisiae (Brewer's yeast) (0)
    No records found.
    Schizosaccharomyces pombe (Fission yeast) (0)
    No records found.
    Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190D80 )
    Organism
    Common Name
    Gene
    AAA Syntenic Ortholog
    Multiple Dmel Genes in this Orthologous Group
    Drosophila erecta
    Drosophila yakuba
    Drosophila ananassae
    Drosophila pseudoobscura pseudoobscura
    Drosophila virilis
    Drosophila mojavensis
    Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091508DA )
    Organism
    Common Name
    Gene
    Multiple Dmel Genes in this Orthologous Group
    Musca domestica
    House fly
    Musca domestica
    House fly
    Musca domestica
    House fly
    Musca domestica
    House fly
    Musca domestica
    House fly
    Glossina morsitans
    Tsetse fly
    Glossina morsitans
    Tsetse fly
    Glossina morsitans
    Tsetse fly
    Glossina morsitans
    Tsetse fly
    Lucilia cuprina
    Australian sheep blowfly
    Lucilia cuprina
    Australian sheep blowfly
    Lucilia cuprina
    Australian sheep blowfly
    Lucilia cuprina
    Australian sheep blowfly
    Mayetiola destructor
    Hessian fly
    Mayetiola destructor
    Hessian fly
    Mayetiola destructor
    Hessian fly
    Mayetiola destructor
    Hessian fly
    Aedes aegypti
    Yellow fever mosquito
    Aedes aegypti
    Yellow fever mosquito
    Aedes aegypti
    Yellow fever mosquito
    Anopheles darlingi
    American malaria mosquito
    Anopheles darlingi
    American malaria mosquito
    Anopheles darlingi
    American malaria mosquito
    Anopheles darlingi
    American malaria mosquito
    Anopheles gambiae
    Malaria mosquito
    Anopheles gambiae
    Malaria mosquito
    Anopheles gambiae
    Malaria mosquito
    Anopheles gambiae
    Malaria mosquito
    Anopheles gambiae
    Malaria mosquito
    Anopheles gambiae
    Malaria mosquito
    Anopheles gambiae
    Malaria mosquito
    Anopheles gambiae
    Malaria mosquito
    Culex quinquefasciatus
    Southern house mosquito
    Culex quinquefasciatus
    Southern house mosquito
    Culex quinquefasciatus
    Southern house mosquito
    Culex quinquefasciatus
    Southern house mosquito
    Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0PR4 )
    Organism
    Common Name
    Gene
    Multiple Dmel Genes in this Orthologous Group
    Bombyx mori
    Silkmoth
    Bombyx mori
    Silkmoth
    Bombyx mori
    Silkmoth
    Bombyx mori
    Silkmoth
    Bombyx mori
    Silkmoth
    Bombyx mori
    Silkmoth
    Bombyx mori
    Silkmoth
    Bombyx mori
    Silkmoth
    Bombyx mori
    Silkmoth
    Bombyx mori
    Silkmoth
    Danaus plexippus
    Monarch butterfly
    Danaus plexippus
    Monarch butterfly
    Danaus plexippus
    Monarch butterfly
    Danaus plexippus
    Monarch butterfly
    Danaus plexippus
    Monarch butterfly
    Danaus plexippus
    Monarch butterfly
    Danaus plexippus
    Monarch butterfly
    Danaus plexippus
    Monarch butterfly
    Danaus plexippus
    Monarch butterfly
    Danaus plexippus
    Monarch butterfly
    Danaus plexippus
    Monarch butterfly
    Danaus plexippus
    Monarch butterfly
    Danaus plexippus
    Monarch butterfly
    Danaus plexippus
    Monarch butterfly
    Heliconius melpomene
    Postman butterfly
    Heliconius melpomene
    Postman butterfly
    Heliconius melpomene
    Postman butterfly
    Heliconius melpomene
    Postman butterfly
    Heliconius melpomene
    Postman butterfly
    Heliconius melpomene
    Postman butterfly
    Heliconius melpomene
    Postman butterfly
    Heliconius melpomene
    Postman butterfly
    Heliconius melpomene
    Postman butterfly
    Heliconius melpomene
    Postman butterfly
    Heliconius melpomene
    Postman butterfly
    Heliconius melpomene
    Postman butterfly
    Apis florea
    Little honeybee
    Apis florea
    Little honeybee
    Apis florea
    Little honeybee
    Apis florea
    Little honeybee
    Apis florea
    Little honeybee
    Apis florea
    Little honeybee
    Apis florea
    Little honeybee
    Apis florea
    Little honeybee
    Apis florea
    Little honeybee
    Apis florea
    Little honeybee
    Apis florea
    Little honeybee
    Apis florea
    Little honeybee
    Apis florea
    Little honeybee
    Apis florea
    Little honeybee
    Apis florea
    Little honeybee
    Apis mellifera
    Western honey bee
    Apis mellifera
    Western honey bee
    Apis mellifera
    Western honey bee
    Apis mellifera
    Western honey bee
    Apis mellifera
    Western honey bee
    Apis mellifera
    Western honey bee
    Apis mellifera
    Western honey bee
    Apis mellifera
    Western honey bee
    Apis mellifera
    Western honey bee
    Apis mellifera
    Western honey bee
    Apis mellifera
    Western honey bee
    Apis mellifera
    Western honey bee
    Apis mellifera
    Western honey bee
    Apis mellifera
    Western honey bee
    Apis mellifera
    Western honey bee
    Bombus impatiens
    Common eastern bumble bee
    Bombus impatiens
    Common eastern bumble bee
    Bombus impatiens
    Common eastern bumble bee
    Bombus impatiens
    Common eastern bumble bee
    Bombus impatiens
    Common eastern bumble bee
    Bombus impatiens
    Common eastern bumble bee
    Bombus impatiens
    Common eastern bumble bee
    Bombus impatiens
    Common eastern bumble bee
    Bombus impatiens
    Common eastern bumble bee
    Bombus impatiens
    Common eastern bumble bee
    Bombus impatiens
    Common eastern bumble bee
    Bombus impatiens
    Common eastern bumble bee
    Bombus impatiens
    Common eastern bumble bee
    Bombus impatiens
    Common eastern bumble bee
    Bombus impatiens
    Common eastern bumble bee
    Bombus terrestris
    Buff-tailed bumblebee
    Bombus terrestris
    Buff-tailed bumblebee
    Bombus terrestris
    Buff-tailed bumblebee
    Bombus terrestris
    Buff-tailed bumblebee
    Bombus terrestris
    Buff-tailed bumblebee
    Bombus terrestris
    Buff-tailed bumblebee
    Bombus terrestris
    Buff-tailed bumblebee
    Bombus terrestris
    Buff-tailed bumblebee
    Bombus terrestris
    Buff-tailed bumblebee
    Bombus terrestris
    Buff-tailed bumblebee
    Bombus terrestris
    Buff-tailed bumblebee
    Bombus terrestris
    Buff-tailed bumblebee
    Bombus terrestris
    Buff-tailed bumblebee
    Bombus terrestris
    Buff-tailed bumblebee
    Linepithema humile
    Argentine ant
    Linepithema humile
    Argentine ant
    Linepithema humile
    Argentine ant
    Linepithema humile
    Argentine ant
    Linepithema humile
    Argentine ant
    Linepithema humile
    Argentine ant
    Linepithema humile
    Argentine ant
    Linepithema humile
    Argentine ant
    Linepithema humile
    Argentine ant
    Linepithema humile
    Argentine ant
    Linepithema humile
    Argentine ant
    Linepithema humile
    Argentine ant
    Megachile rotundata
    Alfalfa leafcutting bee
    Megachile rotundata
    Alfalfa leafcutting bee
    Megachile rotundata
    Alfalfa leafcutting bee
    Megachile rotundata
    Alfalfa leafcutting bee
    Megachile rotundata
    Alfalfa leafcutting bee
    Megachile rotundata
    Alfalfa leafcutting bee
    Megachile rotundata
    Alfalfa leafcutting bee
    Megachile rotundata
    Alfalfa leafcutting bee
    Megachile rotundata
    Alfalfa leafcutting bee
    Megachile rotundata
    Alfalfa leafcutting bee
    Megachile rotundata
    Alfalfa leafcutting bee
    Megachile rotundata
    Alfalfa leafcutting bee
    Megachile rotundata
    Alfalfa leafcutting bee
    Nasonia vitripennis
    Parasitic wasp
    Nasonia vitripennis
    Parasitic wasp
    Nasonia vitripennis
    Parasitic wasp
    Nasonia vitripennis
    Parasitic wasp
    Nasonia vitripennis
    Parasitic wasp
    Nasonia vitripennis
    Parasitic wasp
    Nasonia vitripennis
    Parasitic wasp
    Nasonia vitripennis
    Parasitic wasp
    Nasonia vitripennis
    Parasitic wasp
    Nasonia vitripennis
    Parasitic wasp
    Nasonia vitripennis
    Parasitic wasp
    Nasonia vitripennis
    Parasitic wasp
    Dendroctonus ponderosae
    Mountain pine beetle
    Dendroctonus ponderosae
    Mountain pine beetle
    Dendroctonus ponderosae
    Mountain pine beetle
    Dendroctonus ponderosae
    Mountain pine beetle
    Dendroctonus ponderosae
    Mountain pine beetle
    Dendroctonus ponderosae
    Mountain pine beetle
    Dendroctonus ponderosae
    Mountain pine beetle
    Dendroctonus ponderosae
    Mountain pine beetle
    Dendroctonus ponderosae
    Mountain pine beetle
    Dendroctonus ponderosae
    Mountain pine beetle
    Dendroctonus ponderosae
    Mountain pine beetle
    Dendroctonus ponderosae
    Mountain pine beetle
    Dendroctonus ponderosae
    Mountain pine beetle
    Dendroctonus ponderosae
    Mountain pine beetle
    Dendroctonus ponderosae
    Mountain pine beetle
    Dendroctonus ponderosae
    Mountain pine beetle
    Tribolium castaneum
    Red flour beetle
    Tribolium castaneum
    Red flour beetle
    Tribolium castaneum
    Red flour beetle
    Tribolium castaneum
    Red flour beetle
    Tribolium castaneum
    Red flour beetle
    Tribolium castaneum
    Red flour beetle
    Tribolium castaneum
    Red flour beetle
    Tribolium castaneum
    Red flour beetle
    Tribolium castaneum
    Red flour beetle
    Tribolium castaneum
    Red flour beetle
    Tribolium castaneum
    Red flour beetle
    Tribolium castaneum
    Red flour beetle
    Tribolium castaneum
    Red flour beetle
    Pediculus humanus
    Human body louse
    Pediculus humanus
    Human body louse
    Pediculus humanus
    Human body louse
    Pediculus humanus
    Human body louse
    Pediculus humanus
    Human body louse
    Pediculus humanus
    Human body louse
    Pediculus humanus
    Human body louse
    Pediculus humanus
    Human body louse
    Pediculus humanus
    Human body louse
    Pediculus humanus
    Human body louse
    Pediculus humanus
    Human body louse
    Pediculus humanus
    Human body louse
    Pediculus humanus
    Human body louse
    Pediculus humanus
    Human body louse
    Rhodnius prolixus
    Kissing bug
    Rhodnius prolixus
    Kissing bug
    Rhodnius prolixus
    Kissing bug
    Rhodnius prolixus
    Kissing bug
    Rhodnius prolixus
    Kissing bug
    Rhodnius prolixus
    Kissing bug
    Rhodnius prolixus
    Kissing bug
    Rhodnius prolixus
    Kissing bug
    Rhodnius prolixus
    Kissing bug
    Cimex lectularius
    Bed bug
    Cimex lectularius
    Bed bug
    Cimex lectularius
    Bed bug
    Cimex lectularius
    Bed bug
    Cimex lectularius
    Bed bug
    Cimex lectularius
    Bed bug
    Cimex lectularius
    Bed bug
    Cimex lectularius
    Bed bug
    Cimex lectularius
    Bed bug
    Cimex lectularius
    Bed bug
    Acyrthosiphon pisum
    Pea aphid
    Acyrthosiphon pisum
    Pea aphid
    Acyrthosiphon pisum
    Pea aphid
    Acyrthosiphon pisum
    Pea aphid
    Acyrthosiphon pisum
    Pea aphid
    Acyrthosiphon pisum
    Pea aphid
    Acyrthosiphon pisum
    Pea aphid
    Acyrthosiphon pisum
    Pea aphid
    Acyrthosiphon pisum
    Pea aphid
    Acyrthosiphon pisum
    Pea aphid
    Acyrthosiphon pisum
    Pea aphid
    Zootermopsis nevadensis
    Nevada dampwood termite
    Zootermopsis nevadensis
    Nevada dampwood termite
    Zootermopsis nevadensis
    Nevada dampwood termite
    Zootermopsis nevadensis
    Nevada dampwood termite
    Zootermopsis nevadensis
    Nevada dampwood termite
    Zootermopsis nevadensis
    Nevada dampwood termite
    Zootermopsis nevadensis
    Nevada dampwood termite
    Zootermopsis nevadensis
    Nevada dampwood termite
    Zootermopsis nevadensis
    Nevada dampwood termite
    Zootermopsis nevadensis
    Nevada dampwood termite
    Zootermopsis nevadensis
    Nevada dampwood termite
    Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0FMW )
    Organism
    Common Name
    Gene
    Multiple Dmel Genes in this Orthologous Group
    Strigamia maritima
    European centipede
    Strigamia maritima
    European centipede
    Strigamia maritima
    European centipede
    Strigamia maritima
    European centipede
    Strigamia maritima
    European centipede
    Strigamia maritima
    European centipede
    Strigamia maritima
    European centipede
    Ixodes scapularis
    Black-legged tick
    Ixodes scapularis
    Black-legged tick
    Ixodes scapularis
    Black-legged tick
    Ixodes scapularis
    Black-legged tick
    Ixodes scapularis
    Black-legged tick
    Ixodes scapularis
    Black-legged tick
    Ixodes scapularis
    Black-legged tick
    Ixodes scapularis
    Black-legged tick
    Ixodes scapularis
    Black-legged tick
    Ixodes scapularis
    Black-legged tick
    Ixodes scapularis
    Black-legged tick
    Ixodes scapularis
    Black-legged tick
    Ixodes scapularis
    Black-legged tick
    Ixodes scapularis
    Black-legged tick
    Stegodyphus mimosarum
    African social velvet spider
    Stegodyphus mimosarum
    African social velvet spider
    Stegodyphus mimosarum
    African social velvet spider
    Stegodyphus mimosarum
    African social velvet spider
    Stegodyphus mimosarum
    African social velvet spider
    Tetranychus urticae
    Two-spotted spider mite
    Tetranychus urticae
    Two-spotted spider mite
    Tetranychus urticae
    Two-spotted spider mite
    Tetranychus urticae
    Two-spotted spider mite
    Tetranychus urticae
    Two-spotted spider mite
    Tetranychus urticae
    Two-spotted spider mite
    Daphnia pulex
    Water flea
    Daphnia pulex
    Water flea
    Daphnia pulex
    Water flea
    Daphnia pulex
    Water flea
    Daphnia pulex
    Water flea
    Daphnia pulex
    Water flea
    Daphnia pulex
    Water flea
    Daphnia pulex
    Water flea
    Daphnia pulex
    Water flea
    Daphnia pulex
    Water flea
    Daphnia pulex
    Water flea
    Daphnia pulex
    Water flea
    Daphnia pulex
    Water flea
    Daphnia pulex
    Water flea
    Daphnia pulex
    Water flea
    Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0QR8 )
    Organism
    Common Name
    Gene
    Multiple Dmel Genes in this Orthologous Group
    Strongylocentrotus purpuratus
    Purple sea urchin
    Strongylocentrotus purpuratus
    Purple sea urchin
    Strongylocentrotus purpuratus
    Purple sea urchin
    Strongylocentrotus purpuratus
    Purple sea urchin
    Strongylocentrotus purpuratus
    Purple sea urchin
    Strongylocentrotus purpuratus
    Purple sea urchin
    Ciona intestinalis
    Vase tunicate
    Ciona intestinalis
    Vase tunicate
    Paralogs
    Paralogs (via DIOPT v8.0)
    Drosophila melanogaster (Fruit fly) (52)
    5 of 10
    5 of 10
    5 of 10
    5 of 10
    5 of 10
    5 of 10
    5 of 10
    5 of 10
    5 of 10
    5 of 10
    4 of 10
    4 of 10
    4 of 10
    4 of 10
    4 of 10
    4 of 10
    4 of 10
    4 of 10
    4 of 10
    4 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    1 of 10
    Human Disease Associations
    FlyBase Human Disease Model Reports
      Disease Model Summary Ribbon
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Allele
      Disease
      Evidence
      References
      Potential Models Based on Orthology ( 0 )
      Human Ortholog
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Allele
      Disease
      Interaction
      References
      Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
      Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
      Homo sapiens (Human)
      Gene name
      Score
      OMIM
      OMIM Phenotype
      DO term
      Complementation?
      Transgene?
      Functional Complementation Data
      Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
      Interactions
      Summary of Physical Interactions
      esyN Network Diagram
      Show neighbor-neighbor interactions:
      Select Layout:
      Legend:
      Protein
      RNA
      Selected Interactor(s)
      Interactions Browser

      Please see the Physical Interaction reports below for full details
      protein-protein
      Physical Interaction
      Assay
      References
      Summary of Genetic Interactions
      esyN Network Diagram
      Starting gene(s)
      Interaction type
      Interacting gene(s)
      Reference
      Starting gene(s)
      Interaction type
      Interacting gene(s)
      Reference
      External Data
      Linkouts
      Pathways
      Signaling Pathways (FlyBase)
      Metabolic Pathways
      External Data
      Linkouts
      Genomic Location and Detailed Mapping Data
      Chromosome (arm)
      2R
      Recombination map
      2-55
      Cytogenetic map
      Sequence location
      FlyBase Computed Cytological Location
      Cytogenetic map
      Evidence for location
      Experimentally Determined Cytological Location
      Cytogenetic map
      Notes
      References
      Experimentally Determined Recombination Data
      Location
      Left of (cM)
      Right of (cM)
      Notes
      Stocks and Reagents
      Stocks (3)
      Genomic Clones (51)
      cDNA Clones (21)
       

      Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

      cDNA clones, fully sequenced
      BDGP DGC clones
        Other clones
        Drosophila Genomics Resource Center cDNA clones

        For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

          cDNA Clones, End Sequenced (ESTs)
          BDGP DGC clones
          RNAi and Array Information
          Linkouts
          GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
          Antibody Information
          Laboratory Generated Antibodies
           
          Commercially Available Antibodies
           
          Other Information
          Relationship to Other Genes
          Source for database identify of

          Source for identity of: dpr21 CG42596

          Source for database merge of
          Additional comments
          Other Comments

          New annotation (CG42596) in release 5.19 of the genome annotation.

          Origin and Etymology
          Discoverer
          Etymology
          Identification
          External Crossreferences and Linkouts ( 29 )
          Sequence Crossreferences
          NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
          GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
          RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
          UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
          Other crossreferences
          DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
          EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
          FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
          FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
          FlyMine - An integrated database for Drosophila genomics
          GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
          iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
          KEGG Genes - Molecular building blocks of life in the genomic space.
          MARRVEL_MODEL - MARRVEL (model organism gene)
          modMine - A data warehouse for the modENCODE project
          Synonyms and Secondary IDs (4)
          Datasets (0)
          Study focus (0)
          Experimental Role
          Project
          Project Type
          Title
          References (20)