FlyBase Gene Report: Dmel\CG34353

General Information

Symbol

Dmel\CG34353

Species

D. melanogaster

Name

Annotation Symbol

CG34353

Feature Type

protein_coding_gene

FlyBase ID

FBgn0085382

Gene Model Status

Current

Stock Availability

13 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

98B2-98B5

Sequence location

3R:27,767,966..27,905,843 [-]

Recombination map

3-94

RefSeq locus

NT_033777 REGION:27767966..27905843

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (7 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables axon guidance receptor activity

inferred from biological aspect of ancestor with PANTHER:PTN002895063

(GO Reference Genome Project, 2011-)

Biological Process (3 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in gravitaxis

inferred from mutant phenotype

(Armstrong et al., 2006)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

involved_in homophilic cell-cell adhesion

inferred from biological aspect of ancestor with PANTHER:PTN002895062

(GO Reference Genome Project, 2011-)

involved_in synapse organization

inferred from biological aspect of ancestor with PANTHER:PTN002895063

(GO Reference Genome Project, 2011-)

Cellular Component (3 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

is_active_in axon

inferred from biological aspect of ancestor with PANTHER:PTN002895063

(GO Reference Genome Project, 2011-)

is_active_in neuronal cell body

inferred from biological aspect of ancestor with PANTHER:PTN002895063

(GO Reference Genome Project, 2011-)

is_active_in plasma membrane

inferred from biological aspect of ancestor with PANTHER:PTN002895062

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

KLINGON SUBFAMILY OF WIRINS

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

KLINGON SUBFAMILY OF WIRINS -: Wirins are members of a widely distributed family of two- and three-Ig domain molecules that mediate axonal guidance, synapse targeting, and other neuronal wiring-related functions. The Klingon subfamily expanded within hexapods, resulting in four paralogs in D. melanogaster. (Adapted from FBrf0245249.)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\CG34353 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry A0A0B4LI09)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.49

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

CG34353-RA

FBtr0112563

NM_001104479

3450

566

CG34353-RB

FBtr0305292

NM_001260413

5004

566

CG34353-RC

FBtr0339321

NM_001300642

5049

581

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

CG34353-PA

FBpp0111475

62.3

566

9.20

FBpp0293835

62.3

566

9.20

FBpp0308425

63.8

581

8.93

A0A0B4LI09

NP_001287571

AHN57570

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

566 aa isoforms: CG34353-PA, CG34353-PB

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CG34353 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

CG34353_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.54

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\CG34353 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\CG34353

View exonic expression by tissue for Dmel\CG34353

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

5740590/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0085382

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0085382

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0085382

Flygut - An atlas of the Drosophila adult midgut

FBgn0085382

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 11 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 14 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of CG34353

Transgenic constructs containing regulatory region of CG34353

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 5 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Scer\GAL4^Mef2.PR

CG34353^GD6319

partially lethal - majority die, with Scer\GAL4^pnr-MD237

CG34353^GD6319

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

viable, with Scer\GAL4^GMR71G10, Spyo\Cas9^{UAS.Tag:NLS(Unk)}

CG34353^WKO.3-A2

viable, with Scer\GAL4^Mef2.PR

viable, with Scer\GAL4^pnr-MD237

Other Phenotypes

Allele

abnormal gravitaxis

CG34353^G6

abnormal neuroanatomy | pupal stage, with Scer\GAL4^GMR71G10, Spyo\Cas9^{UAS.Tag:NLS(Unk)}

CG34353^WKO.3-A2

some die during pupal stage, with Scer\GAL4^pnr-MD237

CG34353^GD6319

visible, with Scer\GAL4^pnr-MD237

CG34353^GD6319

Phenotype manifest in

Allele

axon | pupal stage, with Scer\GAL4^GMR71G10, Spyo\Cas9^{UAS.Tag:NLS(Unk)}

CG34353^WKO.3-A2

gamma Kenyon cell | pupal stage, with Scer\GAL4^GMR71G10, Spyo\Cas9^{UAS.Tag:NLS(Unk)}

CG34353^WKO.3-A2

trichogen cell, with Scer\GAL4^pnr-MD237

CG34353^GD6319

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (88)

Hsap\LSAMP

4 of 14

Yes

3 of 14

3 of 14

3 of 14

3 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\FCRL2

1 of 14

Yes

Hsap\FCRL5

1 of 14

Yes

Hsap\FGFRL1

1 of 14

Hsap\FSTL5

1 of 14

Yes

Hsap\GPA33

1 of 14

Yes

Hsap\HAVCR2

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\JAM2

1 of 14

Yes

Hsap\JAML

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\USH2A

1 of 14

Hsap\VCAM1

1 of 14

Yes

Hsap\VSIG10L2

1 of 14

Hsap\VSIG10L

1 of 14

Yes

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (63)

Rnor\Lsamp

4 of 14

Yes

3 of 14

3 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

Yes

Rnor\Btnl7

1 of 14

Rnor\Btnl8

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\Havcr2

1 of 14

Yes

Rnor\Igdcc4

1 of 14

Rnor\Igsf5

1 of 14

Yes

Rnor\Igsf9

1 of 14

Rnor\Igsf10

1 of 14

Rnor\Jam2

1 of 14

Yes

Rnor\Jaml

1 of 14

Rnor\Kazald1

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\Mag

1 of 14

Yes

Rnor\Musk

1 of 14

Rnor\Mybpc2

1 of 14

Rnor\Myot

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\Pxdn

1 of 14

Rnor\Scn4b

1 of 14

Yes

Rnor\Siglec8

1 of 14

Rnor\Siglec10

1 of 14

Rnor\Siglec15

1 of 14

Yes

Rnor\Tmigd1

1 of 14

Rnor\Tyro3

1 of 14

Yes

Rnor\Vcam1

1 of 14

Yes

Mus musculus (laboratory mouse) (69)

Mmus\Iglon5

3 of 14

Yes

Mmus\Lsamp

3 of 14

Yes

Mmus\Negr1

3 of 14

Yes

Mmus\Ntm

3 of 14

Yes

Mmus\Opcml

3 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

Yes

Mmus\Btnl4

1 of 14

Yes

Mmus\Btnl6

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Mmus\Cd86

1 of 14

Yes

Mmus\Cd300lg

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Mmus\Dcc

1 of 14

Mmus\Emb

1 of 14

Mmus\Esam

1 of 14

Yes

Mmus\Fgfrl1

1 of 14

Mmus\Flt4

1 of 14

Mmus\Gpa33

1 of 14

Yes

Mmus\Havcr1

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Mmus\Musk

1 of 14

Mmus\Mybpc2

1 of 14

Mmus\Myot

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Mmus\Siglec1

1 of 14

Mmus\Siglec15

1 of 14

Yes

Mmus\Timd2

1 of 14

Yes

Mmus\Ttn

1 of 14

Mmus\Tyro3

1 of 14

Yes

Mmus\Vcam1

1 of 14

Yes

Xenopus tropicalis (Western clawed frog) (41)

Xtro\iglon5

2 of 13

Yes

Xtro\lsamp

2 of 13

Yes

Xtro\cadm2

1 of 13

Xtro\ceacam8l

1 of 13

Xtro\clmp

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\map3k1

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\rplp0

1 of 13

Xtro\siglec15

1 of 13

Yes

Xtro\slc35g1

1 of 13

Xtro\spata1

1 of 13

Yes

Xtro\speg

1 of 13

Xtro\tmigd1

1 of 13

Yes

Xtro\tyro3

1 of 13

Yes

Xtro\vsig10

1 of 13

Yes

Xtro\XB5805949

1 of 13

Yes

Danio rerio (Zebrafish) (104)

Drer\negr1

4 of 14

Yes

Drer\iglon5

3 of 14

Drer\opcml

3 of 14

Drer\cadm1a

2 of 14

Yes

Drer\cadm1b

2 of 14

Yes

Drer\cadm4

2 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\dicp1.3-4

1 of 14

Yes

Drer\dicp1.16

1 of 14

Yes

Drer\dicp1.17

1 of 14

Yes

Drer\dicp2.1

1 of 14

Yes

Drer\dicp2.2

1 of 14

Yes

Drer\dicp3.1

1 of 14

Yes

Drer\dicp3.3

1 of 14

Yes

Drer\dscaml1

1 of 14

Drer\emb

1 of 14

Drer\esama

1 of 14

Yes

Drer\esamb

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\l1camb

1 of 14

Drer\LOC100148735

1 of 14

Drer\LOC100333752

1 of 14

Yes

Drer\LOC101883325

1 of 14

Drer\LOC103909439

1 of 14

Drer\LOC110438862

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\mdga1

1 of 14

Yes

Drer\mertka

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\scn2b

1 of 14

Yes

Drer\sdk1a

1 of 14

Drer\si:ch73-22o12.1

1 of 14

Drer\si:ch73-208g10.1

1 of 14

Yes

Drer\si:ch211-1f22.12

1 of 14

Drer\si:ch211-66e2.3

1 of 14

Yes

Drer\si:ch211-66e2.5

1 of 14

Yes

Drer\si:ch211-74m13.1

1 of 14

Yes

Drer\si:ch211-159i8.4

1 of 14

Drer\si:ch211-264f5.6

1 of 14

Drer\si:dkey-11p23.7

1 of 14

Yes

Drer\si:dkey-238d18.5

1 of 14

Yes

Drer\siglec15l

1 of 14

Yes

Drer\tmigd1

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\zmp:0000000608

1 of 14

Yes

Caenorhabditis elegans (Nematode, roundworm) (22)

Cele\wrk-1

7 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Anopheles gambiae (African malaria mosquito) (88)

Agam\AgaP_AGAP002628

12 of 12

Yes

5 of 12

5 of 12

5 of 12

4 of 12

Yes

4 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (0)

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:CG34353. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (71)

CG7166

8 of 13

klg

8 of 13

wrapper

6 of 13

Ama

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

Lac

3 of 13

babos

2 of 13

bdl

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

rst

2 of 13

sdk

2 of 13

tutl

2 of 13

Bsg

1 of 13

btl

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

fra

1 of 13

hbs

1 of 13

ImpL2

1 of 13

Nrg

1 of 13

Obsc

1 of 13

otk

1 of 13

Ppn

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

sls

1 of 13

sns

1 of 13

Strn-Mlck

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

LSAMP; limbic system associated membrane protein

4 of 14

603241

IGLON5; IgLON family member 5

3 of 14

618861

NEGR1; neuronal growth regulator 1

3 of 14

613173

NTM; neurotrimin

3 of 14

607938

OPCML; opioid binding protein/cell adhesion molecule like

3 of 14

600632

OVARIAN CANCER

ovarian cancer

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

625221

DroID - A comprehensive database of gene and protein interactions.

FBgn0085382

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-94

Cytogenetic map

98B2-98B5

Sequence location

3R:27,767,966..27,905,843 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

98B2-98B5

Limits computationally determined from genome sequence between P{PZ}btz^rL203 and P{PZ}l(3)06487⁰⁶⁴⁸⁷;

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-94

(FlyBase, 2016)

3-91.9

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (13)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

25665

w¹¹¹⁸; Mi{ET1}CG34353^MB08498

58291

y¹ v¹; P{TRiP.HMJ22398}attP40

36387

y¹ w^*; Mi{MIC}CG34353^MI03986

37382

y¹ w^*; Mi{MIC}CG34353^MI03938

44925

y¹ w^*; Mi{MIC}CG34353^MI08106

60534

y¹ w^*; Mi{PT-GFSTF.0}CG34353^{MI03249-GFSTF.0}

82498

y¹ sc^* v¹ sev²¹; P{WKO.3-A2}attP40

36225

y¹ w^*; Mi{MIC}CG34353^MI03249/TM3, Sb¹ Ser¹

Korea

11667

P{EP}CG34353^G17901

NIG-Fly

HMJ22398

y¹ v¹; P{TRiP.HMJ22398}attP40/CyO

VDRC

v102326

P{KK111343}VIE-260B

v39319

w¹¹¹⁸; P{GD15788}v39319

More stocks available...

Genomic Clones (87)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (5)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0085382

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0085382

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Shows particularly robust cycling of transcription in adult heads, as assessed by expression analysis using high density oligonucleotide arrays with probe generated during three 12-point time course experiments over the course of 6 days.

(Claridge-Chang et al., 2001)

Relationship to Other Genes

Source for database merge of

Source for merge of: CG12274 CG12427 CG12873 CG12874 CG12875 CG5566 CG5572

(FlyBase Genome Annotators, 2007)

Additional comments

The CG34353 gene may have been derived from the CG42343 gene by retroposition.

(Pan and Zhang, 2009)

Annotations CG12274, CG12427, CG12873, CG12874, CG12875, CG5566 and CG5572 merged as CG34353 in release 5.2 of the genome annotation.

(FlyBase Genome Annotators, 2007)

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (10)

Reported As

Symbol Synonym

CG12274

(Pan and Zhang, 2009)

CG12427

CG12873

CG12874

CG12875

CG5566

CG5572

lcr

(Hamoudi et al., 2024)

Name Synonyms

CG12274

CG12427

CG12873

CG12874

CG12875

CG5566

CG5572

last caress

(Hamoudi et al., 2024)

Secondary FlyBase IDs

FBgn0039546
FBgn0040615
FBgn0039549
FBgn0039547
FBgn0039545
FBgn0039550
FBgn0039548

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 39 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

5740590

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

A0A0B4LI09

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

A0A0B4LI09

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

5740590/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0085382

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0085382

FlyMine - An integrated database for Drosophila genomics

FBgn0085382

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG34353

MARRVEL_MODEL - MARRVEL (model organism gene)

5740590

Linkouts

BioGRID - A database of protein and genetic interactions.

625221

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0085382

DroID - A comprehensive database of gene and protein interactions.

FBgn0085382

DRSC - Results frm RNAi screens

FBgn0085382

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

CG34353_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0085382

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0085382

Flygut - An atlas of the Drosophila adult midgut

FBgn0085382

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

References (55)

The following external sites may use different assemblies or annotations than FlyBase.

-0.54

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