EG:BACR19J1.1 , CT16627
Ig domain receptor - accumulates in specific synaptic layers of the developing motion detection circuit - necessary for normal optomotor behavior - adherens junctions - tricellular junction protein - regulates vertex dynamics to promote bicellular junction extension - necessary to maintain normal levels of cell bond tension
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Replace with wild type sequence from GenBank accession U88578
Sequence error at position X:730319 (inserted T) leads to premature translation stop in fifth exon. Will be corrected in future release.
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.50
9.4 (longest cDNA)
2231, 2222 (aa); 240 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\sdk using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
sdk localises to the axons and growth cones, where it is concentrated, of developing photoreceptor cells R1-R6, but not R7-R8 in ommatidial precursor clusters. It is present in glial cells that ensheath the axons of developing R7-R8 cells. It is also present in neurons that will go onto to be columnar neurons in the lamina. In the pupa, it localises to five spots in the optic cartridge that likely represent the contacts between the heels of the photoreceptor growth cones.
Comment: low expression in the adult brain cortex
JBrowse - Visual display of RNA-Seq signals
View Dmel\sdk in JBrowsePlease Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
Source for merge of: sdk BcDNA:LD22322
Source for merge of: sdk BcDNA:RE63453
Source for merge of sdk BcDNA:LD22322 was sequence comparison ( date:990717 ).
Source for merge of sdk BcDNA:RE63453 was a shared cDNA ( date:030728 ).
Source for identity of: sdk CG5227