FB2026_02 , released June 18, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
robo1, Nedd4
FlyBase ID
FBig0000123764
Interaction Network
Interactions Browser links
robo1 network
Nedd4 network
Reported Interactions
FBrf0262475-1.coIP.WB
Reference
Sullivan and Bashaw, 2025
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2R+
Participants
Corresponds to
Reported as
Role
Note
robo1 

Robo

bait

GFP tag

Nedd4 

Nedd4

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Mutation of comm PY motifs reduces robo1-Nedd4 interaction. comm-robo1-Nedd4 form a complex. Captured by 3 pairwise interactions.

(Sullivan and Bashaw, 2025)

Source was cell extract of S2R+ cell line; bait produced from transfected construct; prey produced from transfected construct.

(Sullivan and Bashaw, 2025)
External Crossreferences and Linkouts ( 0 )
References (1)