FlyBase Allele Report: Scer\GAL4[c17]

General Information

Symbol

Scer\GAL4^c17

Species

S. cerevisiae

Name

FlyBase ID

FBal0268942

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GawB}c17

Carried in Construct

Also Known As

c17-GAL4, c17, P[Gal4]-c17

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{GawB}c17

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

giant fiber neuron

(Allen et al., 1999)

giant fiber neuron

(Lee and Godenschwege, 2015)

Additional Information

Statement

Reference

ScerGAL4^c17 drives expression in the giant fiber neuron, but not in its postsynaptic target neurons.

(Lee and Godenschwege, 2015)

In adults, expressed in giant fibers and a subset of sensory neurons.

(Allen et al., 1999)

Marker for

giant fiber neuron

(Allen et al., 1999)

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | adult stage | drug conditional, with Rnor\P2rx2^UAS.cLa

(Lima and Miesenbock, 2005)

abnormal neuroanatomy, with DCTN1-p150^Δ.UAS

(Allen et al., 1999)

abnormal neuroanatomy, with Nrg^GPI.UAS

(Godenschwege et al., 2006)

abnormal neuroanatomy, with robo1^UAS.cKa

(Godenschwege et al., 2002)

abnormal neuroanatomy, with robo1^UAS.Tag:MYC

(Godenschwege et al., 2002)

abnormal neuroanatomy, with robo1^{ΔCC2CC3.UAS.Tag:MYC}

(Godenschwege et al., 2002)

abnormal neuroanatomy, with robo2^UAS.Tag:MYC

(Godenschwege et al., 2002)

abnormal neuroanatomy, with robo3^UAS.cSa

(Godenschwege et al., 2002)

abnormal neuroanatomy | heat sensitive, with Sema1a^UAS.cYa

(Murphey et al., 2003)

abnormal neuroanatomy | heat sensitive, with shi^1.UAS

(Murphey et al., 2003)

abnormal neurophysiology, with Ctet\tetX^TNT-LC.UAS

(Allen et al., 1999)

abnormal neurophysiology, with DCTN1-p150^Δ.UAS

(Allen et al., 1999)

abnormal neurophysiology, with Nrg^180.UAS, Nrg⁸⁴⁹

(Godenschwege et al., 2006)

abnormal neurophysiology, with Nrg⁸⁴⁹, Nrg^GPI.UAS

(Godenschwege et al., 2006)

abnormal neurophysiology, with robo1^UAS.Tag:MYC

(Godenschwege et al., 2002)

abnormal neurophysiology | adult stage, with Hsap\YARS1^{153-156delVKQV.UAS}

(Storkebaum et al., 2009)

abnormal neurophysiology | heat sensitive, with Sema1a^UAS.cYa

(Murphey et al., 2003)

abnormal neurophysiology | heat sensitive, with shi^1.UAS

(Murphey et al., 2003)

Phenotype Manifest In

giant fiber neuron, with DCTN1-p150^Δ.UAS

(Allen et al., 1999)

giant fiber neuron, with Hsap\YARS1^{153-156delVKQV.UAS}

(Storkebaum et al., 2009)

giant fiber neuron, with robo1^UAS.cKa

(Godenschwege et al., 2002)

giant fiber neuron, with robo1^UAS.Tag:MYC

(Godenschwege et al., 2002)

giant fiber neuron, with robo2^UAS.Tag:MYC

(Godenschwege et al., 2002)

giant fiber neuron, with robo3^UAS.cSa

(Godenschwege et al., 2002)

giant fiber neuron | heat sensitive, with Sema1a^UAS.cYa

(Murphey et al., 2003)

giant fiber neuron | heat sensitive, with shi^1.UAS

(Murphey et al., 2003)

giant fibers & nerve terminal, with DCTN1-p150^Δ.UAS

(Allen et al., 1999)

giant fibers & synapse, with Ctet\tetX^TNT-LC.UAS

(Allen et al., 1999)

giant fibers & synapse, with DCTN1-p150^Δ.UAS

(Allen et al., 1999)

synapse, with Nrg^GPI.UAS

(Godenschwege et al., 2006)

synapse | adult stage, with robo1^UAS.cKa

(Godenschwege et al., 2002)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^c17, Sema1a^UAS.cYa has abnormal neurophysiology | heat sensitive phenotype, enhanceable by Scer\GAL4^c17/shi^1.UAS

(Murphey et al., 2003)

Scer\GAL4^c17, Sema1a^UAS.cYa has abnormal neuroanatomy | heat sensitive phenotype, enhanceable by Scer\GAL4^c17/shi^1.UAS

(Murphey et al., 2003)

Scer\GAL4^c17, shi^1.UAS has abnormal neurophysiology | heat sensitive phenotype, enhanceable by Scer\GAL4^c17/Sema1a^UAS.cYa

(Murphey et al., 2003)

Scer\GAL4^c17, shi^1.UAS has abnormal neuroanatomy | heat sensitive phenotype, enhanceable by Scer\GAL4^c17/Sema1a^UAS.cYa

(Murphey et al., 2003)

NOT suppressed by

Statement

Reference

Rnor\P2rx2^UAS.cLa, Scer\GAL4^c17 has abnormal locomotor behavior | adult stage | drug conditional phenotype, non-suppressible by norpA^EE5/norpA^EE5

(Lima and Miesenbock, 2005)

Enhancer of

Statement

Reference

Scer\GAL4^c17/shi^1.UAS is an enhancer of abnormal neurophysiology | heat sensitive phenotype of Scer\GAL4^c17, Sema1a^UAS.cYa

(Murphey et al., 2003)

Scer\GAL4^c17/shi^1.UAS is an enhancer of abnormal neuroanatomy | heat sensitive phenotype of Scer\GAL4^c17, Sema1a^UAS.cYa

(Murphey et al., 2003)

Scer\GAL4^c17/Sema1a^UAS.cYa is an enhancer of abnormal neurophysiology | heat sensitive phenotype of Scer\GAL4^c17, shi^1.UAS

(Murphey et al., 2003)

Scer\GAL4^c17/Sema1a^UAS.cYa is an enhancer of abnormal neuroanatomy | heat sensitive phenotype of Scer\GAL4^c17, shi^1.UAS

(Murphey et al., 2003)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^c17, shi^1.UAS has giant fiber neuron | heat sensitive phenotype, enhanceable by Scer\GAL4^c17/Sema1a^UAS.cYa

(Murphey et al., 2003)

Scer\GAL4^c17, Sema1a^UAS.cYa has giant fiber neuron | heat sensitive phenotype, enhanceable by Scer\GAL4^c17/shi^1.UAS

(Murphey et al., 2003)

Enhancer of

Statement

Reference

Scer\GAL4^c17/Sema1a^UAS.cYa is an enhancer of giant fiber neuron | heat sensitive phenotype of Scer\GAL4^c17, shi^1.UAS

(Murphey et al., 2003)

Scer\GAL4^c17/shi^1.UAS is an enhancer of giant fiber neuron | heat sensitive phenotype of Scer\GAL4^c17, Sema1a^UAS.cYa

(Murphey et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^c17/ben^UAS.cUa rescues ben¹

(Uthaman et al., 2008)

nAChRα7^UAS.cFa/Scer\GAL4^c17 rescues nAChRα7¹

(Fayyazuddin et al., 2006)

Scer\GAL4^c17/Nrg^180.UAS rescues Nrg⁸⁴⁹

(Godenschwege et al., 2006)

Fails to rescue

Scer\GAL4^c17/Nrg^GPI.UAS fails to rescue Nrg⁸⁴⁹

(Godenschwege et al., 2006)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

39690

w^*; P{GawB}c17/CyO

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Scer\GAL4^C17

Scer\GAL4^c17

Name Synonyms

Secondary FlyBase IDs

FBal0097144
FBal0230486

References (15)

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