FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\robo1robo1
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General Information
Symbol
Dmel\robo1robo1
Species
D. melanogaster
Name
FlyBase ID
FBal0243798
Feature type
allele
Associated gene
Dmel\robo1
Associated Insertion(s)
TI{TI}robo1robo1
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
recombination
(Spitzweck et al., 2010)
I-SceI
(Spitzweck et al., 2010)
FLPase
(Spitzweck et al., 2010)
I-CreI
(Spitzweck et al., 2010)
ends-in gene targeting
(Spitzweck et al., 2010)
Progenitor genotype
Associated Insertion(s)
TI{TI}robo1robo1
Cytology
Description

The endogenous exons (and intervening small introns) that encode the mature robo1 protein have been replaced with a single exon encoding full length robo1 tagged with Tag:HA. The exon encoding the signal peptide is derived from the targeted robo1 locus.

(Spitzweck et al., 2010)
Allele components
Component
Use(s)
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      roborobo.HR.T:Ivir\HA1 homozygotes do not show the characteristic longitudinal connective phenotypes seen in robo null mutants.

      (Spitzweck et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      robo1robo.HR.T:Ivir\HA1
      robo1robo1
      (Spitzweck et al., 2010)
      roborobo.HR.T:Ivir\HA1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)