FlyBase Allele Report: Scer\GAL4[SG18.1]

Pupal expression is observed in cells with bipolar morphology typical of olfactory neurons. Adult expression is observed in the outer nerve layer of the antennal lobes, and in many antennal glomeruli.

(Ang et al., 2003)

Expression is observed in a majority of sensory neurons plus a subset of neurons in the central nervous system in larvae and adults.

(Sarpal et al., 2003)

Adult expression is observed in olfactory sensory neurons of the third antennal segment, with stronger expression in the coeloconic and trichoid sense organs.

(Jhaveri and Rodrigues, 2002)

Larval expression is observed in a ring pattern on the leg disc, in the dorsal and ventral wing blade region of the wing disc, and in the dorsal and ventral surfaces of the haltere disc. In the third instar, expression is observed in clusters of cells in presumptive antennal segment 3, and in the maxillary palpus region. Pupal expression observed in antennal sensory neurons and in the antennal nerve. Adult expression is observed in the olfactory receptors and the CNS processing centers of the olfactory receptors, specifically in sensory neurons of antennal segment 3 and the maxillary palpus, afferents from those sensilla projecting into the antennal lobe, their interneurons, relay interneurons from the antennal glomeruli to the calyx of the mushroom body, and the calyx of the mushroom body.

(Shyamala and Chopra, 1999)

Marker for

antennal lobe

(Ang et al., 2003, Shyamala and Chopra, 1999)

sensory neuron

(Sarpal et al., 2003, Jhaveri and Rodrigues, 2002, Shyamala and Chopra, 1999)

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

adult antennal lobe, with Wnt5^GS1192

(Yao et al., 2007)

adult antennal lobe commissure, with Abl^EP3101

(Jhaveri et al., 2004)

adult antennal lobe commissure, with Cdc42^V12.UAS

(Jhaveri et al., 2004)

adult antennal lobe commissure, with comm^UAS.cKa

(Jhaveri et al., 2004)

adult antennal lobe commissure, with Rac1^V12.UAS

(Jhaveri and Rodrigues, 2002)

adult antennal lobe commissure, with robo2^EP2582

(Jhaveri et al., 2004)

adult antennal lobe commissure, with Wnt5^GS1192

(Yao et al., 2007)

antennal lobe, with LIMK1^{kd.UAS.Tag:MYC}

(Ang et al., 2006)

antennal lobe, with LIMK1^UAS.Tag:MYC

(Ang et al., 2006)

antennal lobe, with Pak^{UAS.Tag:Myr(Src64B)}

(Ang et al., 2006)

antennal lobe, with Rac1^V12.UAS

(Jhaveri and Rodrigues, 2002)

antennal lobe glomerulus, with Abl^EP3101

(Jhaveri et al., 2004)

antennal lobe glomerulus, with Cdc42^V12.UAS

(Jhaveri et al., 2004)

antennal lobe glomerulus, with comm^UAS.cKa

(Jhaveri et al., 2004)

antennal lobe glomerulus, with robo1^UAS.cKa

(Jhaveri et al., 2004)

antennal lobe glomerulus, with robo2^EP2582

(Jhaveri et al., 2004)

antennal lobe glomerulus | ectopic, with LIMK1^{kd.UAS.Tag:MYC}

(Ang et al., 2006)

antennal lobe glomerulus DM6, with LIMK1^{kd.UAS.Tag:MYC}

(Ang et al., 2006)

antennal lobe glomerulus VA6, with LIMK1^{kd.UAS.Tag:MYC}

(Ang et al., 2006)

glomerulus | ectopic, with Cdc42^V12.UAS

(Jhaveri et al., 2004)

olfactory neuron & antennal lobe, with robo3^{UAS.Tag:HA,Tag:SS(wg)}

(Jhaveri et al., 2004)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1 has abnormal neuroanatomy phenotype, suppressible by tsr^S3A.cA.UAS, Scer\GAL4^SG18.1

(Ang et al., 2006)

Pak^{UAS.Tag:Myr(Src64B)}, Scer\GAL4^SG18.1 has abnormal neuroanatomy phenotype, suppressible by Df(1)LIMK1-5

(Ang et al., 2006)

NOT suppressed by

Statement

Reference

LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1 has abnormal neuroanatomy phenotype, non-suppressible by tsr^UAS.cAa, Scer\GAL4^SG18.1

(Ang et al., 2006)

Enhancer of

Statement

Reference

Scer\GAL4^SG18.1/Wnt5^UAS.cFa is an enhancer of abnormal neuroanatomy | adult stage phenotype of drl²

(Yao et al., 2007)

Suppressor of

Statement

Reference

tsr^S3A.cA.UAS, Scer\GAL4^SG18.1 is a suppressor of abnormal neuroanatomy phenotype of LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1

(Ang et al., 2006)

NOT Suppressor of

Statement

Reference

tsr^UAS.cAa, Scer\GAL4^SG18.1 is a non-suppressor of abnormal neuroanatomy phenotype of LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1

(Ang et al., 2006)

Phenotype Manifest In

Suppressed by

Statement

Reference

LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1 has antennal lobe phenotype, suppressible by tsr^S3A.cA.UAS, Scer\GAL4^SG18.1

(Ang et al., 2006)

LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1 has antennal lobe glomerulus DM6 phenotype, suppressible by tsr^S3A.cA.UAS, Scer\GAL4^SG18.1

(Ang et al., 2006)

LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1 has antennal lobe glomerulus VA6 phenotype, suppressible by tsr^S3A.cA.UAS, Scer\GAL4^SG18.1

(Ang et al., 2006)

LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1 has antennal lobe glomerulus | ectopic phenotype, suppressible by tsr^S3A.cA.UAS, Scer\GAL4^SG18.1

(Ang et al., 2006)

Scer\GAL4^SG18.1, robo2^EP2582 has antennal lobe glomerulus phenotype, suppressible by Df(2R)WMG

(Jhaveri et al., 2004)

Scer\GAL4^SG18.1, robo2^EP2582 has adult antennal lobe commissure phenotype, suppressible by Df(2R)WMG

(Jhaveri et al., 2004)

NOT suppressed by

Statement

Reference

LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1 has antennal lobe phenotype, non-suppressible by tsr^UAS.cAa, Scer\GAL4^SG18.1

(Ang et al., 2006)

LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1 has antennal lobe glomerulus DM6 phenotype, non-suppressible by tsr^UAS.cAa, Scer\GAL4^SG18.1

(Ang et al., 2006)

LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1 has antennal lobe glomerulus VA6 phenotype, non-suppressible by tsr^UAS.cAa, Scer\GAL4^SG18.1

(Ang et al., 2006)

LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1 has antennal lobe glomerulus | ectopic phenotype, non-suppressible by tsr^UAS.cAa, Scer\GAL4^SG18.1

(Ang et al., 2006)

Enhancer of

Statement

Reference

Scer\GAL4^SG18.1/Wnt5^UAS.cFa is an enhancer of adult antennal lobe phenotype of drl²

(Yao et al., 2007)

Suppressor of

Statement

Reference

tsr^S3A.cA.UAS, Scer\GAL4^SG18.1 is a suppressor of antennal lobe phenotype of LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1

(Ang et al., 2006)

Df(1)LIMK1-5/Scer\GAL4^SG18.1 is a suppressor of antennal lobe phenotype of Pak^{UAS.Tag:Myr(Src64B)}

(Ang et al., 2006)

tsr^S3A.cA.UAS, Scer\GAL4^SG18.1 is a suppressor of antennal lobe glomerulus DM6 phenotype of LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1

(Ang et al., 2006)

tsr^S3A.cA.UAS, Scer\GAL4^SG18.1 is a suppressor of antennal lobe glomerulus VA6 phenotype of LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1

(Ang et al., 2006)

tsr^S3A.cA.UAS, Scer\GAL4^SG18.1 is a suppressor of antennal lobe glomerulus | ectopic phenotype of LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1

(Ang et al., 2006)

NOT Suppressor of

Statement

Reference

tsr^UAS.cAa, Scer\GAL4^SG18.1 is a non-suppressor of antennal lobe phenotype of LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1

(Ang et al., 2006)

tsr^UAS.cAa, Scer\GAL4^SG18.1 is a non-suppressor of antennal lobe glomerulus DM6 phenotype of LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1

(Ang et al., 2006)

tsr^UAS.cAa, Scer\GAL4^SG18.1 is a non-suppressor of antennal lobe glomerulus VA6 phenotype of LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1

(Ang et al., 2006)

tsr^UAS.cAa, Scer\GAL4^SG18.1 is a non-suppressor of antennal lobe glomerulus | ectopic phenotype of LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1

(Ang et al., 2006)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Dys^Dp186.UAS, Scer\GAL4^SG18.1, Dys^Dp186.UAS rescues Dys^Dp186.166.3

(Jantrapirom et al., 2019)

Klp64D^UAS.GFP/Scer\GAL4^SG18.1 rescues Klp64D^k1

(Jana et al., 2011)

Klp68D^UAS.YFP/Scer\GAL4^SG18.1 rescues Klp68D^KG03849

(Jana et al., 2011)

Scer\GAL4^SG18.1/Kap3^UAS.cSa rescues Kap3^V6

(Jana et al., 2011)

loj^UAS.N9d/Scer\GAL4^SG18.1 rescues loj⁰⁰⁸⁹⁸

(Boltz et al., 2007)

loj^UAS.N9d/Scer\GAL4^SG18.1 rescues loj⁰⁰⁸⁹⁸/loj⁰⁴⁰²⁶

(Boltz et al., 2007)

Scer\GAL4^SG18.1/Kap3^UAS.cSa rescues Kap3^V5/Kap3^V6

(Sarpal et al., 2003)

Partially rescues

Scer\GAL4^SG18.1/Wnt5^UAS.cFa partially rescues Wnt5⁴⁰⁰

(Yao et al., 2007)

dock^W151K.UAS/Scer\GAL4^SG18.1 partially rescues dock⁰⁴⁷²³

(Ang et al., 2003)

dock^W225K.UAS/Scer\GAL4^SG18.1 partially rescues dock⁰⁴⁷²³

(Ang et al., 2003)

Scer\GAL4^SG18.1/dock^UAS.cRa partially rescues dock⁰⁴⁷²³

(Ang et al., 2003)

Pak^UAS.Tag:MYC/Scer\GAL4^SG18.1 partially rescues Pak¹¹/Pak⁶

(Ang et al., 2003)

Scer\GAL4^SG18.1/dock^R336Q.UAS partially rescues dock⁰⁴⁷²³

(Ang et al., 2003)

Fails to rescue

dock^W48K.UAS/Scer\GAL4^SG18.1 fails to rescue dock⁰⁴⁷²³

(Ang et al., 2003)

Scer\GAL4^SG18.1/ato^UAS.cJa fails to rescue ato¹/Df(3R)p13

(Jhaveri and Rodrigues, 2002)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

6405

108770

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Gal4^SG18.1

(Jana et al., 2011)

Scer\GAL4^SG18.1

Scer\GAL4^SG18

Name Synonyms

Secondary FlyBase IDs

References (17)

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