FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\LIMK1UAS.Tag:MYC
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General Information
Symbol
Dmel\LIMK1UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0194765
Feature type
allele
Associated gene
Dmel\LIMK1
Associated Insertion(s)
Carried in Construct
P{UAS-LIMK1.MYC}
Key Links
Transgenic product class
wild_type
(Ang et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Ang et al., 2006)
Mutagen
in vitro construct
(Ang et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-LIMK1.MYC}
Cytology
Description

UASt regulatory sequences drive expression of LIMK1, which has 2 copies of the Tag:MYC tag at the carboxy terminus.

(Ang et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
LIMK1
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Globose structures appear at the midline of the antennal commissure of animals expressing LIMK1Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4SG18.1, which contains only axons in wild-type animals.

      (Ang et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4RapGAP1-OK6/LIMK1UAS.Tag:MYC partially rescues Df(1)LIMK1-5

      (Ang et al., 2006)
      Fails to rescue

      Scer\GAL4how-24B/LIMK1UAS.Tag:MYC fails to rescue Df(1)LIMK1-5

      (Ang et al., 2006)
      Comments

      Expression of LIMK1Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4OK6 partially rescues the NMJ phenotype of Df(1)LIMK1-5 mutants, as bouton size is less increased than in Df(1)LIMK1-5 mutants that do not express the transgene.

      (Ang et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      LIMK1Scer\UAS.T:Hsap\MYC
      LIMK1UAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)