FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\schs.PR
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General Information
Symbol
Dmel\schs.PR
Species
D. melanogaster
Name
heat shock construct of Rodriguez
FlyBase ID
FBal0032647
Feature type
allele
Associated gene
Dmel\sc
Associated Insertion(s)
Carried in Construct
P{HSSC-3}
Key Links
Transgenic product class
wild_type
(Rodriguez et al., 1990)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Rodriguez et al., 1990)
Mutagen
in vitro construct
(Reddy et al., 1997, Ray and Rodrigues, 1994, Ghysen et al., 1993, Torres and Sanchez, 1991, Rodriguez et al., 1990)
Progenitor genotype
Carried in construct
P{HSSC-3}
Cytology
Description

An Hsp70 promoter drives sc expression.

(Rodriguez et al., 1990)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
sc
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The bristle phenotype seen female D.simulans/D.melanogaster hybrids is significantly rescued by the heat shock induction of schs.PR. The best rescue takes place from heat shocks applied close to the time of formation of the precursors for each bristle.

      (Skaer and Simpson, 2000)

      Flies expressing schs.PR in a Df(1)sc10-1 background have macrochaetae at the dorsocentral and presutural positions. These bristles have normal axon projections.

      (Grillenzoni et al., 1998)

      Expression of schs.PR does not alter the number of olfactory sensilla on the surface of the third antennal segment. Large bristles resembling macrochaetae are produced on the surface of the third antennal segment when schs.PR is expressed using heat shock.

      (Reddy et al., 1997)

      Tp(3;3)iro-1 homozygotes flies carrying schs.PR develop tufts of bristles in the lateral part of the notum (that is normally naked in Tp(3;3)iro-1 homozygotes) after heat shock.

      (Leyns et al., 1996)

      Df(1)sc10-1 flies carrying schs.PR can develop the complete labellum bristle pattern, when they are heat shocked at 0, 6 and 12 hours after puparium formation.

      (Ray and Rodrigues, 1994)

      In the absence of endogenous ac or sc most schs.PvD induced sense organs are wild type and in the correct position on the notum, thoracic pleura, wings and legs.

      (Rodriguez et al., 1990)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      schs.PR rescues scsisB-1/sc10-1

      (Torres and Sanchez, 1991)
      Comments

      Expression of schs.PR during the first two hours of development rescues female scsisB-1/sc10-1 embryos.

      (Torres and Sanchez, 1991)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      I. Rodriguez.

      (Ruiz-Gomez and Ghysen, 1993)
      Comments
      Comments

      Expression of schs.PR during the first three hours of development promotes Sxl-dependent lethality.

      (Torres and Sanchez, 1991)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      schs.PR
      Name Synonyms
      heat shock construct of Rodriguez
      Secondary FlyBase IDs
        References (11)